Head to Head
| Mexico U20 League | 2021/02/18 16:00 | Atletico San Luis U20 v Santos Laguna U20 | W | 0-4 |
| Mexico U20 League | 2020/10/25 17:00 | Santos Laguna U20 v Atletico San Luis U20 | W | 2-1 |
| Mexico U20 League | 2019/09/21 15:00 | Atletico San Luis U20 v Santos Laguna U20 | W | 1-5 |
Home History
| Mexico U20 League | 2021/11/04 15:00 | Unam Pumas U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2021/10/30 14:00 | Queretaro U20 v Santos Laguna U20 | W | 0-5 |
| Mexico U20 League | 2021/10/24 16:00 | Santos Laguna U20 v Toluca U20 | W | 3-0 |
| Mexico U20 League | 2021/10/16 17:00 | Pachuca U20 v Santos Laguna U20 | D | 2-2 |
| Mexico U20 League | 2021/10/02 15:30 | Santos Laguna U20 v Mazatlan FC U20 | W | 4-2 |
| Mexico U20 League | 2021/09/26 15:30 | Santos Laguna U20 v Monterrey U20 | W | 4-1 |
| Mexico U20 League | 2021/09/19 16:00 | Santos Laguna U20 v Puebla U20 | W | 4-2 |
| Mexico U20 League | 2021/09/15 14:00 | Club America U20 v Santos Laguna U20 | W | 0-1 |
Away History
| Mexico U20 League | 2021/11/03 18:00 | Pachuca U20 v Atletico San Luis U20 | W | 1-3 |
| Mexico U20 League | 2021/10/31 15:00 | Atletico San Luis U20 v Monterrey U20 | W | 3-1 |
| Mexico U20 League | 2021/10/24 14:00 | Atletico San Luis U20 v Atlas U20 | L | 0-2 |
| Mexico U20 League | 2021/10/16 14:00 | Atletico San Luis U20 v Club America U20 | W | 1-0 |
| Mexico U20 League | 2021/10/02 14:00 | Leon U20 v Atletico San Luis U20 | L | 2-0 |
| Mexico U20 League | 2021/09/29 14:00 | Atletico San Luis U20 v Tigres U20 | W | 2-1 |
| Mexico U20 League | 2021/09/26 14:00 | Toluca U20 v Atletico San Luis U20 | L | 2-0 |
| Mexico U20 League | 2021/09/21 14:00 | FC Juarez U20 v Atletico San Luis U20 | W | 1-2 |