[5] Roma 0-3 Inter Milan [3] 2021-12-04 17:00
Stadium: Stadio Olimpico Round: 16
Referee: Marco Di Bello Home Manager: Jose Mourinho Away Manager: Simone Inzaghi
Head to Head
| Italy Serie A | 2021/05/12 18:45 | Inter Milan v Roma | L | 3-1 |
| Italy Serie A | 2021/01/10 11:30 | Roma v Inter Milan | D | 2-2 |
| Italy Serie A | 2020/07/19 19:45 | Roma v Inter Milan | D | 2-2 |
| Italy Serie A | 2019/12/06 19:45 | Inter Milan v Roma | D | 0-0 |
| Italy Serie A | 2019/04/20 18:30 | Inter Milan v Roma | D | 1-1 |
| Italy Serie A | 2018/12/02 19:30 | Roma v Inter Milan | D | 2-2 |
| Italy Serie A | 2018/01/21 19:45 | Inter Milan v Roma | D | 1-1 |
| Italy Serie A | 2017/08/26 18:45 | Roma v Inter Milan | L | 1-3 |
Home History
| Italy Serie A | 2021/12/01 17:30 | Bologna v Roma | L | 1-0 |
| Italy Serie A | 2021/11/28 17:00 | Roma v Torino | W | 1-0 |
| UEFA Conference League | 2021/11/25 20:00 | Roma v FC Zorya Lugansk | W | 4-0 |
| Italy Serie A | 2021/11/21 19:45 | Genoa v Roma | W | 0-2 |
| Italy Serie A | 2021/11/07 11:30 | Venezia v Roma | L | 3-2 |
| UEFA Conference League | 2021/11/04 20:00 | Roma v Bodo/Glimt | D | 2-2 |
| Italy Serie A | 2021/10/31 19:45 | Roma v AC Milan | L | 1-2 |
| Italy Serie A | 2021/10/27 18:45 | Cagliari v Roma | W | 1-2 |
Away History
| Italy Serie A | 2021/12/01 17:30 | Inter Milan v Spezia | W | 2-0 |
| Italy Serie A | 2021/11/27 19:45 | Venezia v Inter Milan | W | 0-2 |
| UEFA Champions League | 2021/11/24 17:45 | Inter Milan v Shakhtar Donetsk | W | 2-0 |
| Italy Serie A | 2021/11/21 17:00 | Inter Milan v Napoli | W | 3-2 |
| Italy Serie A | 2021/11/07 19:45 | AC Milan v Inter Milan | D | 1-1 |
| UEFA Champions League | 2021/11/03 20:00 | Sheriff Tiraspol v Inter Milan | W | 1-3 |
| Italy Serie A | 2021/10/31 11:30 | Inter Milan v Udinese | W | 2-0 |
| Italy Serie A | 2021/10/27 18:45 | Empoli v Inter Milan | W | 0-2 |