Home History
| England National League | 2021/08/30 14:00 | Wealdstone v Southend | D | 0-0 |
| England National League | 2021/08/28 16:20 | Southend v Stockport | L | 0-1 |
| England National League | 2021/08/21 14:00 | Kings Lynn Town v Southend | W | 0-1 |
| UK Friendlies | 2021/08/07 14:00 | Ebbsfleet United v Southend | D | 1-1 |
| UK Friendlies | 2021/08/04 18:00 | Southend v Brentford XI | L | 2-3 |
| UK Friendlies | 2021/07/31 14:00 | Dartford v Southend | D | 2-2 |
| England League 2 | 2021/05/08 14:00 | Southend v Newport County | D | 1-1 |
| England League 2 | 2021/05/01 14:00 | Barrow v Southend | W | 1-2 |
Away History
| England National League | 2021/08/30 18:30 | Wrexham v Notts County | D | 1-1 |
| England National League | 2021/08/28 14:00 | Eastleigh v Wrexham | W | 0-2 |
| England National League | 2021/08/21 14:00 | Solihull Moors v Wrexham | D | 2-2 |
| UK Friendlies | 2021/08/07 14:00 | Spennymoor Town v Wrexham | D | 2-2 |
| UK Friendlies | 2021/08/03 12:00 | Fleetwood Town XI v Wrexham | W | 0-4 |
| UK Friendlies | 2021/07/31 14:00 | Tamworth v Wrexham | W | 0-5 |
| England National League | 2021/05/29 11:30 | Dag & Red v Wrexham | D | 1-1 |
| England National League | 2021/05/22 14:00 | Wrexham v Kings Lynn Town | W | 5-3 |