Home History
| England National League | 2021/10/02 14:00 | Solihull Moors v Southend | L | 2-0 |
| England National League | 2021/09/18 14:00 | Torquay v Southend | L | 1-0 |
| England National League | 2021/09/14 18:45 | Southend v Aldershot | L | 2-3 |
| England National League | 2021/09/11 14:00 | Halifax v Southend | L | 3-1 |
| England National League | 2021/09/04 14:00 | Southend v Wrexham | D | 2-2 |
| England National League | 2021/08/30 14:00 | Wealdstone v Southend | D | 0-0 |
| England National League | 2021/08/28 16:20 | Southend v Stockport | L | 0-1 |
| England National League | 2021/08/21 14:00 | Kings Lynn Town v Southend | W | 0-1 |
Away History
| England National League | 2021/10/02 16:20 | Eastleigh v Boreham Wood | D | 1-1 |
| England National League | 2021/09/25 14:00 | Eastleigh v Woking | W | 3-2 |
| England National League | 2021/09/18 14:00 | Grimsby v Eastleigh | L | 2-0 |
| England National League | 2021/09/14 18:45 | Eastleigh v Dover | W | 4-1 |
| England National League | 2021/09/11 14:00 | Barnet v Eastleigh | D | 1-1 |
| England National League | 2021/09/04 14:00 | Eastleigh v Kings Lynn Town | D | 3-3 |
| England National League | 2021/08/30 14:00 | Bromley v Eastleigh | L | 3-0 |
| England National League | 2021/08/28 14:00 | Eastleigh v Wrexham | L | 0-2 |