[7] America de Cali 2-3 Jaguares de Cordoba [12] 2021-09-18 21:00
Stadium: Olimpico Pascual Guerrero Round: 10
Referee: Bismark Elias Santiago Pitalua Home Manager: Juan Carlos Osorio Away Manager: Cesar Torres
Head to Head
| Colombia Cup | 2021/09/01 22:30 | Jaguares de Cordoba v America de Cali | W | 6-7 |
| Colombia Cup | 2021/08/26 23:00 | America de Cali v Jaguares de Cordoba | D | 0-0 |
| Colombia Primera A | 2021/04/10 22:40 | Jaguares de Cordoba v America de Cali | D | 0-0 |
| Colombia Primera A | 2020/01/29 21:05 | Jaguares de Cordoba v America de Cali | D | 2-2 |
| Colombia Primera A | 2019/09/15 20:30 | Jaguares de Cordoba v America de Cali | D | 2-2 |
| Colombia Primera A | 2019/03/24 23:00 | America de Cali v Jaguares de Cordoba | W | 1-0 |
| Colombia Primera A | 2018/09/05 23:00 | America de Cali v Jaguares de Cordoba | W | 2-1 |
| Colombia Primera A | 2018/03/16 01:00 | Jaguares de Cordoba v America de Cali | L | 1-0 |
Home History
| Colombia Cup | 2021/09/16 01:00 | Deportivo Cali v America de Cali | L | 1-0 |
| Colombia Primera A | 2021/09/11 23:05 | Deportivo Cali v America de Cali | W | 0-1 |
| Colombia Cup | 2021/09/08 23:00 | America de Cali v Deportivo Cali | D | 2-2 |
| Colombia Primera A | 2021/09/04 21:00 | America de Cali v Deportes Quindio | L | 0-1 |
| Colombia Cup | 2021/09/01 22:30 | Jaguares de Cordoba v America de Cali | W | 6-7 |
| Colombia Primera A | 2021/08/29 23:05 | Independiente Santa Fe v America de Cali | D | 1-1 |
| Colombia Cup | 2021/08/26 23:00 | America de Cali v Jaguares de Cordoba | D | 0-0 |
| Colombia Primera A | 2021/08/21 00:30 | America de Cali v Patriotas FC | D | 0-0 |
Away History
| Colombia Primera A | 2021/09/11 00:40 | Jaguares de Cordoba v Independiente Medellin | L | 0-1 |
| Colombia Primera A | 2021/09/04 23:05 | La Equidad v Jaguares de Cordoba | L | 1-0 |
| Colombia Cup | 2021/09/01 22:30 | Jaguares de Cordoba v America de Cali | L | 6-7 |
| Colombia Primera A | 2021/08/30 01:10 | Jaguares de Cordoba v Deportes Tolima | L | 0-3 |
| Colombia Cup | 2021/08/26 23:00 | America de Cali v Jaguares de Cordoba | D | 0-0 |
| Colombia Primera A | 2021/08/22 21:00 | Aguilas Doradas v Jaguares de Cordoba | W | 1-2 |
| Colombia Primera A | 2021/08/15 21:00 | Jaguares de Cordoba v Junior | D | 1-1 |
| Colombia Primera A | 2021/08/10 00:40 | Atletico Bucaramanga v Jaguares de Cordoba | W | 0-1 |