[13] Junior 4-2 Once Caldas [17] 2021-08-21 23:05
Stadium: Estadio Metropolitano Roberto Melendez Round: 6
Referee: Andres Jose Rojas Noguera Home Manager: Luis Amaranto Perea Mosquera Away Manager: Eduardo Lara Lozano
Head to Head
| Colombia Primera A | 2021/01/25 22:30 | Once Caldas v Junior | W | 1-2 |
| Colombia Primera A | 2020/02/16 23:10 | Junior v Once Caldas | D | 0-0 |
| Colombia Primera A | 2019/08/24 22:00 | Junior v Once Caldas | L | 0-1 |
| Colombia Primera A | 2019/03/02 22:00 | Once Caldas v Junior | W | 0-1 |
| Colombia Primera A | 2018/09/16 22:15 | Once Caldas v Junior | L | 1-0 |
| Colombia Primera A | 2018/03/24 23:00 | Junior v Once Caldas | W | 3-0 |
| Colombia Primera A | 2017/08/26 23:00 | Once Caldas v Junior | L | 3-2 |
| Colombia Primera A | 2017/08/20 22:15 | Junior v Once Caldas | W | 3-0 |
Home History
| Colombia Primera A | 2021/08/15 21:00 | Jaguares de Cordoba v Junior | D | 1-1 |
| Colombia Primera A | 2021/08/08 23:05 | Junior v Deportes Tolima | D | 0-0 |
| Colombia Primera A | 2021/08/01 01:10 | Independiente Medellin v Junior | D | 0-0 |
| Colombia Primera A | 2021/07/25 22:40 | Junior v Envigado FC | W | 1-0 |
| Copa Sudamericana | 2021/07/22 00:30 | Libertad Asuncion v Junior | W | 0-1 |
| Colombia Primera A | 2021/07/17 20:30 | America de Cali v Junior | L | 3-1 |
| Copa Sudamericana | 2021/07/15 00:30 | Junior v Libertad Asuncion | L | 3-4 |
| Colombia Primera A | 2021/06/13 18:30 | Millonarios v Junior | L | 2-0 |
Away History
| Colombia Primera A | 2021/08/16 01:10 | Once Caldas v Deportivo Pereira | L | 0-1 |
| Colombia Primera A | 2021/08/07 20:00 | America de Cali v Once Caldas | L | 1-0 |
| Colombia Cup | 2021/08/04 22:40 | Once Caldas v Independiente Medellin | L | 1-3 |
| Colombia Primera A | 2021/08/01 23:05 | Once Caldas v Millonarios | L | 0-2 |
| Colombia Cup | 2021/07/29 01:05 | Independiente Medellin v Once Caldas | D | 1-1 |
| Colombia Primera A | 2021/07/24 22:40 | Jaguares de Cordoba v Once Caldas | D | 1-1 |
| Colombia Primera A | 2021/07/19 23:00 | Once Caldas v Atletico Huila | W | 1-0 |
| Colombia Primera A | 2021/04/18 21:30 | Once Caldas v Independiente Medellin | W | 2-0 |