Home History
| Germany Bundesliga II Women | 2021/12/15 14:00 | FC Ingolstadt Women v RB Leipzig Women | W | 2-3 |
| Germany Bundesliga II Women | 2021/12/12 10:00 | FSV Gutersloh 2009 Women v RB Leipzig Women | W | 1-4 |
| Germany Bundesliga II Women | 2021/11/21 10:00 | Nurnberg Women v RB Leipzig Women | L | 4-3 |
| Germany Bundesliga II Women | 2021/11/07 10:00 | RB Leipzig Women v Elversberg Women | W | 3-0 |
| Germany Bundesliga II Women | 2021/10/17 09:00 | BV Borussia Bocholt Women v RB Leipzig Women | W | 1-9 |
| Germany Bundesliga II Women | 2021/10/10 09:00 | RB Leipzig Women v SG Andernach Women | L | 0-1 |
| Germany Bundesliga II Women | 2021/10/03 09:00 | SV Meppen Women v RB Leipzig Women | L | 5-0 |
| Germany DFB Pokal Women | 2021/09/26 12:00 | RB Leipzig Women v Bayer Leverkusen Women | L | 1-3 |
Away History
| Germany Bundesliga II Women | 2021/12/12 10:00 | MSV Duisburg Women v Henstedt-Ulzburg Women | W | 4-2 |
| Germany Bundesliga II Women | 2021/12/05 10:00 | Nurnberg Women v MSV Duisburg Women | W | 1-2 |
| Germany Bundesliga II Women | 2021/11/14 10:00 | Elversberg Women v MSV Duisburg Women | W | 1-5 |
| Germany Bundesliga II Women | 2021/11/07 13:00 | MSV Duisburg Women v BV Borussia Bocholt Women | W | 3-0 |
| Germany Bundesliga II Women | 2021/10/17 12:00 | SG Andernach Women v MSV Duisburg Women | L | 3-1 |
| Germany Bundesliga II Women | 2021/10/10 12:00 | MSV Duisburg Women v SV Meppen Women | W | 3-0 |
| Germany Bundesliga II Women | 2021/10/03 09:00 | Eintracht Frankfurt II Women v MSV Duisburg Women | W | 1-3 |
| Germany DFB Pokal Women | 2021/09/27 16:30 | MSV Duisburg Women v Wolfsburg Women | L | 1-3 |