Home History
| USA USL League Two | 2021/07/26 00:30 | Des Moines Menace v Portland Timbers U23 | W | 2-0 |
| USA USL League Two | 2021/07/24 01:30 | Des Moines Menace v Kalamazoo FC | W | 2-1 |
| USA USL League Two | 2021/07/19 00:00 | Des Moines Menace v Flint City Bucks | W | 1-0 |
| USA USL League Two | 2021/07/17 00:00 | Des Moines Menace v Texas United | W | 5-0 |
| USA USL League Two | 2021/07/11 00:00 | Des Moines Menace v St. Louis Scott Gallagher SC | W | 5-1 |
| USA USL League Two | 2021/07/08 00:00 | Des Moines Menace v Chicago FC United | W | 4-0 |
| USA USL League Two | 2021/06/30 23:00 | Chicago FC United v Des Moines Menace | L | 2-0 |
| USA USL League Two | 2021/06/25 00:00 | FC Wichita v Des Moines Menace | W | 1-3 |
Away History
| USA USL League Two | 2021/07/26 00:00 | Salem City FC v Western Mass Pioneers | W | 3-1 |
| USA USL League Two | 2021/07/24 00:00 | South Georgia Tormenta FC II v Salem City FC | W | 2-4 |
| USA USL League Two | 2021/07/18 23:00 | SC United Bantams v Salem City FC | W | 1-2 |
| USA USL League Two | 2021/07/17 13:00 | Salem City FC v Tampa Bay United | W | 5-0 |
| USA USL League Two | 2021/07/09 23:00 | Virginia Beach Utd v Salem City FC | W | 0-6 |
| USA USL League Two | 2021/07/07 23:00 | Salem City FC v West Virginia United | W | 4-2 |
| USA USL League Two | 2021/06/30 23:00 | West Virginia United v Salem City FC | D | 2-2 |
| USA USL League Two | 2021/06/26 17:00 | North Carolina FC II v Salem City FC | W | 0-1 |