Head to Head
| England Premier League 2 | 2020/02/03 19:00 | Southampton U23 v Wolverhampton U23 | L | 1-0 |
| England Premier League 2 | 2019/09/27 18:00 | Wolverhampton U23 v Southampton U23 | L | 1-2 |
| England Premier League 2 | 2019/03/11 19:00 | Wolverhampton U23 v Southampton U23 | W | 3-1 |
| England Premier League 2 | 2018/10/19 18:00 | Southampton U23 v Wolverhampton U23 | L | 3-2 |
| England Premier League 2 | 2017/12/11 19:00 | Southampton U23 v Wolverhampton U23 | W | 2-4 |
| England Premier League 2 | 2017/08/21 18:00 | Wolverhampton U23 v Southampton U23 | W | 3-0 |
Home History
| England Premier League 2 | 2021/10/01 18:00 | Aston Villa U23 v Wolverhampton U23 | D | 0-0 |
| England Premier League 2 | 2021/09/27 17:00 | Wolverhampton U23 v Sunderland U23 | L | 1-3 |
| England Premier League 2 | 2021/09/20 18:00 | Wolverhampton U23 v Fulham U23 | W | 2-1 |
| England U23 Premier League Cup | 2021/09/15 18:00 | Exeter U23 v Wolverhampton U23 | W | 2-3 |
| England Premier League 2 | 2021/09/10 18:00 | Burnley U23 v Wolverhampton U23 | D | 1-1 |
| England U23 Premier League Cup | 2021/09/03 13:00 | Wolverhampton U23 v West Ham U23 | W | 1-0 |
| England Premier League 2 | 2021/08/27 18:00 | Wolverhampton U23 v Nottm Forest U23 | W | 1-0 |
| England Premier League 2 | 2021/08/23 18:00 | Reading U23 v Wolverhampton U23 | L | 3-0 |
Away History
| England Premier League 2 | 2021/10/01 15:00 | Southampton U23 v Stoke U23 | D | 1-1 |
| England Premier League 2 | 2021/09/27 12:30 | Birmingham U23 v Southampton U23 | L | 3-2 |
| England U23 Premier League Cup | 2021/09/23 18:00 | Southampton U23 v West Brom U23 | L | 0-6 |
| England Premier League 2 | 2021/09/19 13:00 | Southampton U23 v Burnley U23 | L | 0-2 |
| England Premier League 2 | 2021/09/10 18:00 | Fulham U23 v Southampton U23 | L | 3-0 |
| England U23 Premier League Cup | 2021/09/02 18:00 | Arsenal U23 v Southampton U23 | D | 1-1 |
| England Premier League 2 | 2021/08/29 11:00 | Middlesbrough U23 v Southampton U23 | L | 2-1 |
| England Premier League 2 | 2021/08/23 18:00 | Nottm Forest U23 v Southampton U23 | D | 0-0 |