Head to Head
| England Premier League 2 | 2019/03/01 19:00 | Southampton U23 v Reading U23 | W | 1-2 |
| England Premier League 2 | 2018/09/29 12:00 | Reading U23 v Southampton U23 | W | 2-0 |
| England Premier League 2 | 2017/12/18 12:30 | Reading U23 v Southampton U23 | D | 1-1 |
| England Premier League 2 | 2017/01/06 13:00 | Reading U23 v Southampton U23 | W | 4-2 |
| England EFL Trophy | 2016/12/21 19:00 | Southampton U23 v Reading U23 | W | 4-5 |
| England Premier League 2 | 2016/09/12 18:00 | Southampton U23 v Reading U23 | L | 3-1 |
Home History
| England Premier League 2 | 2021/10/15 18:00 | Fulham U23 v Reading U23 | L | 3-0 |
| England U23 Premier League Cup | 2021/10/11 12:00 | Reading U23 v Norwich U23 | W | 3-2 |
| England Premier League 2 | 2021/10/04 18:00 | Reading U23 v Birmingham U23 | D | 1-1 |
| England Premier League 2 | 2021/09/27 18:00 | Burnley U23 v Reading U23 | L | 3-1 |
| England Premier League 2 | 2021/09/20 18:00 | Reading U23 v Norwich U23 | D | 3-3 |
| England Premier League 2 | 2021/09/12 18:00 | Reading U23 v Nottm Forest U23 | L | 0-2 |
| England U23 Premier League Cup | 2021/09/08 13:00 | Charlton U23 v Reading U23 | L | 3-0 |
| England Premier League 2 | 2021/08/29 14:00 | Stoke U23 v Reading U23 | W | 1-2 |
Away History
| England Premier League 2 | 2021/10/18 11:00 | Wolverhampton U23 v Southampton U23 | W | 0-1 |
| England Premier League 2 | 2021/10/01 15:00 | Southampton U23 v Stoke U23 | D | 1-1 |
| England Premier League 2 | 2021/09/27 12:30 | Birmingham U23 v Southampton U23 | L | 3-2 |
| England U23 Premier League Cup | 2021/09/23 18:00 | Southampton U23 v West Brom U23 | L | 0-6 |
| England Premier League 2 | 2021/09/19 13:00 | Southampton U23 v Burnley U23 | L | 0-2 |
| England Premier League 2 | 2021/09/10 18:00 | Fulham U23 v Southampton U23 | L | 3-0 |
| England U23 Premier League Cup | 2021/09/02 18:00 | Arsenal U23 v Southampton U23 | D | 1-1 |
| England Premier League 2 | 2021/08/29 11:00 | Middlesbrough U23 v Southampton U23 | L | 2-1 |