Head to Head
| England Premier League 2 | 2019/05/03 18:00 | Southampton U23 v Aston Villa U23 | W | 2-0 |
| England Premier League 2 | 2018/12/07 19:00 | Aston Villa U23 v Southampton U23 | L | 2-1 |
| England Premier League 2 | 2018/09/21 18:00 | Southampton U23 v Aston Villa U23 | L | 0-1 |
| England Premier League 2 | 2018/01/15 19:00 | Southampton U23 v Aston Villa U23 | L | 1-4 |
| England Premier League 2 | 2017/09/11 18:00 | Aston Villa U23 v Southampton U23 | L | 4-0 |
Home History
| England Premier League 2 | 2021/10/25 18:00 | Reading U23 v Southampton U23 | W | 0-1 |
| England Premier League 2 | 2021/10/18 11:00 | Wolverhampton U23 v Southampton U23 | W | 0-1 |
| England Premier League 2 | 2021/10/01 15:00 | Southampton U23 v Stoke U23 | D | 1-1 |
| England Premier League 2 | 2021/09/27 12:30 | Birmingham U23 v Southampton U23 | L | 3-2 |
| England U23 Premier League Cup | 2021/09/23 18:00 | Southampton U23 v West Brom U23 | L | 0-6 |
| England Premier League 2 | 2021/09/19 13:00 | Southampton U23 v Burnley U23 | L | 0-2 |
| England Premier League 2 | 2021/09/10 18:00 | Fulham U23 v Southampton U23 | L | 3-0 |
| England U23 Premier League Cup | 2021/09/02 18:00 | Arsenal U23 v Southampton U23 | D | 1-1 |
Away History
| England Premier League 2 | 2021/10/22 17:00 | Aston Villa U23 v Sunderland U23 | L | 2-3 |
| England Premier League 2 | 2021/10/16 11:00 | Birmingham U23 v Aston Villa U23 | W | 1-2 |
| England Premier League 2 | 2021/10/01 18:00 | Aston Villa U23 v Wolverhampton U23 | D | 0-0 |
| England Premier League 2 | 2021/09/27 18:00 | Stoke U23 v Aston Villa U23 | W | 0-8 |
| England Premier League 2 | 2021/09/17 17:00 | Aston Villa U23 v West Brom U23 | W | 4-2 |
| England Premier League 2 | 2021/09/10 18:00 | Norwich U23 v Aston Villa U23 | L | 4-2 |
| England Premier League 2 | 2021/08/27 18:00 | Aston Villa U23 v Fulham U23 | D | 1-1 |
| England Premier League 2 | 2021/08/20 18:00 | Middlesbrough U23 v Aston Villa U23 | W | 1-2 |