Head to Head
| England Premier League 2 | 2021/11/05 12:00 | Southampton U23 v Newcastle U23 | L | 5-0 |
| England Premier League 2 | 2019/05/13 18:00 | Southampton U23 v Newcastle U23 | L | 2-1 |
| England U23 Premier League Cup | 2019/02/08 19:00 | Newcastle U23 v Southampton U23 | W | 3-0 |
| England Premier League 2 | 2018/12/14 19:00 | Southampton U23 v Newcastle U23 | L | 2-1 |
| England U23 Premier League Cup | 2018/11/09 19:00 | Southampton U23 v Newcastle U23 | D | 1-1 |
| England Premier League 2 | 2018/09/14 18:00 | Newcastle U23 v Southampton U23 | L | 0-1 |
| England Premier League 2 | 2018/02/19 19:00 | Newcastle U23 v Southampton U23 | L | 1-5 |
| England Premier League 2 | 2017/10/16 18:00 | Southampton U23 v Newcastle U23 | L | 6-2 |
Home History
| England Premier League 2 | 2022/04/18 18:00 | Wolverhampton U23 v Newcastle U23 | L | 4-2 |
| England Premier League 2 | 2022/04/08 18:00 | Burnley U23 v Newcastle U23 | L | 5-1 |
| England Premier League 2 | 2022/04/01 18:00 | Middlesbrough U23 v Newcastle U23 | L | 4-2 |
| England Premier League 2 | 2022/03/28 17:00 | Newcastle U23 v West Brom U23 | W | 4-3 |
| England Premier League 2 | 2022/03/21 19:00 | Stoke U23 v Newcastle U23 | L | 2-1 |
| England Premier League 2 | 2022/03/14 19:00 | Newcastle U23 v Birmingham U23 | W | 1-0 |
| England U23 Premier League Cup | 2022/03/04 14:00 | Fulham U23 v Newcastle U23 | L | 2-0 |
| England Premier League 2 | 2022/02/28 19:00 | Norwich U23 v Newcastle U23 | W | 3-4 |
Away History
| England Premier League 2 | 2022/04/02 10:00 | Burnley U23 v Southampton U23 | L | 2-1 |
| England Premier League 2 | 2022/03/25 12:00 | Southampton U23 v Wolverhampton U23 | L | 2-4 |
| England Premier League 2 | 2022/03/20 11:00 | Southampton U23 v Reading U23 | W | 2-1 |
| England Premier League 2 | 2022/03/11 14:00 | Aston Villa U23 v Southampton U23 | D | 2-2 |
| England Premier League 2 | 2022/02/26 15:00 | Southampton U23 v Nottm Forest U23 | W | 4-2 |
| England Premier League 2 | 2022/02/21 19:00 | Southampton U23 v Birmingham U23 | L | 2-3 |
| England Premier League 2 | 2022/02/07 19:00 | West Brom U23 v Southampton U23 | W | 0-1 |
| England U23 Premier League Cup | 2022/01/27 12:00 | Southampton U23 v Bournemouth U23 | L | 0-1 |