Head to Head
| England Premier League 2 | 2021/11/21 12:00 | Sunderland U23 v Southampton U23 | L | 3-2 |
| England Premier League 2 | 2019/04/29 18:00 | Southampton U23 v Sunderland U23 | W | 5-1 |
| England Premier League 2 | 2018/10/28 12:30 | Sunderland U23 v Southampton U23 | W | 0-2 |
| England Premier League 2 | 2016/12/09 12:00 | Southampton U23 v Sunderland U23 | L | 0-2 |
| England Premier League 2 | 2016/08/28 12:00 | Sunderland U23 v Southampton U23 | L | 3-0 |
Home History
| England Premier League 2 | 2022/04/25 18:00 | Newcastle U23 v Southampton U23 | W | 2-4 |
| England Premier League 2 | 2022/04/02 10:00 | Burnley U23 v Southampton U23 | L | 2-1 |
| England Premier League 2 | 2022/03/25 12:00 | Southampton U23 v Wolverhampton U23 | L | 2-4 |
| England Premier League 2 | 2022/03/20 11:00 | Southampton U23 v Reading U23 | W | 2-1 |
| England Premier League 2 | 2022/03/11 14:00 | Aston Villa U23 v Southampton U23 | D | 2-2 |
| England Premier League 2 | 2022/02/26 15:00 | Southampton U23 v Nottm Forest U23 | W | 4-2 |
| England Premier League 2 | 2022/02/21 19:00 | Southampton U23 v Birmingham U23 | L | 2-3 |
| England Premier League 2 | 2022/02/07 19:00 | West Brom U23 v Southampton U23 | W | 0-1 |
Away History
| England Premier League 2 | 2022/04/25 18:00 | Sunderland U23 v Birmingham U23 | W | 2-1 |
| England Premier League 2 | 2022/04/18 18:00 | Sunderland U23 v Aston Villa U23 | L | 1-3 |
| England Premier League 2 | 2022/04/01 18:00 | Norwich U23 v Sunderland U23 | D | 1-1 |
| England Premier League 2 | 2022/03/21 19:00 | Sunderland U23 v Burnley U23 | L | 0-2 |
| England Premier League 2 | 2022/03/14 19:00 | Nottm Forest U23 v Sunderland U23 | L | 3-0 |
| England Premier League 2 | 2022/02/28 19:00 | Sunderland U23 v Stoke U23 | L | 0-3 |
| England Premier League 2 | 2022/02/21 19:00 | Sunderland U23 v West Brom U23 | L | 0-1 |
| England U23 Premier League Cup | 2022/02/14 19:00 | Sunderland U23 v Wigan U23 | D | 2-2 |