Home History
| England Premier League 2 | 2016/09/19 18:00 | Southampton U21 v Leicester U21 | D | 2-2 |
| England EFL Trophy | 2016/08/30 18:45 | Charlton v Southampton U21 | L | 5-4 |
| England Premier League 2 | 2016/08/22 18:00 | Southampton U21 v Man Utd U21 | W | 2-0 |
| England Premier League 2 | 2016/08/14 12:00 | Liverpool U21 v Southampton U21 | W | 1-4 |
| England U21 Premier League Cup | 2015/04/20 18:00 | Southampton U21 v Blackburn U21 | W | 2-1 |
| England U21 Premier League Cup | 2015/04/13 18:00 | Blackburn U21 v Southampton U21 | D | 0-0 |
| England U21 Premier League Cup | 2015/03/05 19:00 | Southampton U21 v Derby U21 | W | 4-2 |
| England U21 Premier League Cup | 2015/02/12 19:00 | Southampton U21 v Watford U21 | W | 3-2 |
Away History
| England EFL Trophy | 2016/08/30 18:45 | Bristol Rovers v Reading U21 | W | 2-3 |
| England Premier League 2 | 2016/08/26 18:00 | Reading U21 v Man City U21 | W | 3-2 |
| England Premier League 2 | 2016/08/22 13:00 | Reading U21 v Tottenham U21 | L | 1-4 |
| England Premier League 2 | 2016/08/12 18:00 | Arsenal U21 v Reading U21 | W | 0-2 |
| England U21 Premier League Cup | 2015/02/03 13:00 | Huddersfield U21 v Reading U21 | W | 0-1 |