| Colombia Regional League | 2021/07/18 19:21 | CD Gallegol v Real Santuario | L | 3-2 |
| Colombia Regional League | 2021/07/04 17:16 | CD Los Del Sur v Real Santuario | W | 2-4 |
| Colombia Regional League | 2021/06/26 19:13 | Real Santuario v Club Deportivo La Chalaca | D | 2-2 |
| Colombia Regional League | 2021/06/20 18:00 | Aguilas Doradas v Real Santuario | L | 4-2 |
| Colombia Regional League | 2021/06/06 15:00 | Sellos Colombianos v Real Santuario | W | 0-1 |