[30] John Isner 4-6,6-3,6-4 Cristian Garin [20] 2021-08-11 15:00
Stadium: Grandstand Round: 25 Ground: Hardcourt outdoor
Head to Head
| ATP Paris | 2019/10/30 12:15 | Cristian Garin v John Isner | 7-6,7-6 |
| ATP Montreal | 2019/08/07 21:15 | Cristian Garin v John Isner | 6-3,6-4 |
Home History
| ATP Toronto | 2021/08/10 17:25 | John Isner v Alejandro Davidovich Fokina | 6-4,6-1 |
| ATP Atlanta | 2021/08/01 21:00 | Brandon Nakashima v John Isner | 6-7,5-7 |
| ATP Atlanta | 2021/07/31 23:00 | Taylor Fritz v John Isner | 6-7,7-5,3-6 |
| ATP Atlanta | 2021/07/31 00:00 | John Isner v Christopher O'Connell | 7-6,6-7,6-4 |
| ATP Atlanta | 2021/07/29 23:00 | John Isner v Jack Sock | 7-6,6-4 |
| ATP Atlanta | 2021/07/27 19:00 | John Isner v Jeffrey John Wolf | 6-4,6-7,6-4 |
| ATP Los Cabos | 2021/07/24 03:00 | Brandon Nakashima v John Isner | 7-5,6-4 |
| ATP Los Cabos | 2021/07/23 02:30 | Alex Bolt v John Isner | 3-6,4-6 |
Away History
| ATP Gstaad | 2021/07/23 08:30 | Hugo Gaston v Cristian Garin | 6-4,1-6,7-6 |
| ATP Gstaad | 2021/07/21 15:30 | Marc Polmans v Cristian Garin | 3-6,0-6 |
| ATP Bastad | 2021/07/16 10:45 | Federico Coria v Cristian Garin | 6-4,4-6,6-2 |
| ATP Bastad | 2021/07/14 11:25 | Pedro Martinez v Cristian Garin | 3-6,3-6 |
| Wimbledon | 2021/07/05 12:30 | Novak Djokovic v Cristian Garin | 6-2,6-4,6-2 |
| Wimbledon | 2021/07/02 11:05 | Cristian Garin v Pedro Martinez | 6-4,6-3,4-6,6-4 |
| Wimbledon | 2021/07/01 10:00 | Cristian Garin v Marc Polmans | 7-6,6-2,2-6,7-6 |
| Wimbledon | 2021/06/29 17:25 | Cristian Garin v Bernabe Zapata Miralles | 6-7,6-3,3-6,6-3,6-2 |