[2] Olympiakos 0-0 Panathinaikos [6] 2021-10-03 17:30
Stadium: Karaiskakis Stadium Round: 5
Referee: Slavko Vincic Home Manager: Pedro Rui Mota Vieira Martins Away Manager: Ivan Jovanovic
Head to Head
| Greece Super League 1 | 2021/05/16 16:30 | Panathinaikos v Olympiakos | W | 1-4 |
| Greece Super League 1 | 2021/04/11 16:30 | Olympiakos v Panathinaikos | W | 3-1 |
| Greece Super League 1 | 2021/02/14 17:30 | Panathinaikos v Olympiakos | L | 2-1 |
| Greece Super League 1 | 2020/11/21 17:30 | Olympiakos v Panathinaikos | W | 1-0 |
| Greece Super League 1 | 2020/07/05 18:30 | Panathinaikos v Olympiakos | D | 0-0 |
| Greece Super League 1 | 2020/06/21 18:30 | Olympiakos v Panathinaikos | W | 3-0 |
| Greece Super League 1 | 2020/01/05 17:30 | Olympiakos v Panathinaikos | W | 1-0 |
| Greece Super League 1 | 2019/09/22 17:30 | Panathinaikos v Olympiakos | D | 1-1 |
Home History
| UEFA Europa League | 2021/09/30 16:45 | Fenerbahce v Olympiakos | W | 0-3 |
| Greece Super League 1 | 2021/09/26 13:00 | Asteras Tripolis v Olympiakos | W | 0-2 |
| Greece Super League 1 | 2021/09/22 15:15 | Olympiakos v Apollon Smyrnis | W | 4-1 |
| Greece Super League 1 | 2021/09/19 17:30 | Lamia v Olympiakos | W | 1-2 |
| UEFA Europa League | 2021/09/16 19:00 | Olympiakos v Antwerp | W | 2-1 |
| Greece Super League 1 | 2021/09/12 17:30 | Olympiakos v Atromitos Athinon | D | 0-0 |
| Europe Friendlies | 2021/09/03 17:00 | Aris Salonika v Olympiakos | D | 1-1 |
| UEFA Europa League Qualifying | 2021/08/26 18:45 | Slovan Bratislava v Olympiakos | D | 2-2 |
Away History
| Greece Super League 1 | 2021/09/26 13:00 | Panathinaikos v Volos NFC | W | 5-1 |
| Greece Super League 1 | 2021/09/22 17:30 | Aris Salonika v Panathinaikos | L | 1-0 |
| Greece Super League 1 | 2021/09/18 17:30 | Giannina v Panathinaikos | L | 1-0 |
| Greece Super League 1 | 2021/09/11 17:30 | Panathinaikos v Apollon Smyrnis | W | 4-0 |
| World Club Friendlies | 2021/09/04 16:30 | Panathinaikos v Lamia | W | 3-2 |
| Europe Friendlies | 2021/08/28 17:00 | Panathinaikos v Asteras Tripolis | D | 1-1 |
| World Club Friendlies | 2021/08/21 14:30 | Panathinaikos v Panetolikos | L | 1-2 |
| Elite Club Friendlies | 2021/08/14 18:30 | AC Milan v Panathinaikos | L | 2-1 |