[4] Orlando Pirates 0-2 Mamelodi Sundowns [1] 2021-09-25 13:00
Stadium: Orlando Stadium Round: 1
Referee: Home Manager: Mandla Ncikazi Away Manager: Steve Komphela
Head to Head
| South Africa Premier | 2021/05/02 13:00 | Orlando Pirates v Mamelodi Sundowns | L | 0-3 |
| South Africa Cup | 2021/04/15 16:00 | Mamelodi Sundowns v Orlando Pirates | L | 4-1 |
| South Africa Premier | 2021/01/02 13:30 | Mamelodi Sundowns v Orlando Pirates | L | 1-0 |
| South Africa Premier | 2020/08/11 16:00 | Mamelodi Sundowns v Orlando Pirates | D | 0-0 |
| South Africa Premier | 2020/01/15 17:30 | Orlando Pirates v Mamelodi Sundowns | W | 1-0 |
| South Africa Premier | 2019/04/01 17:30 | Orlando Pirates v Mamelodi Sundowns | D | 0-0 |
| South Africa Premier | 2018/11/10 13:30 | Mamelodi Sundowns v Orlando Pirates | D | 0-0 |
| South Africa Premier | 2018/01/13 13:30 | Mamelodi Sundowns v Orlando Pirates | W | 1-3 |
Home History
| South Africa Premier | 2021/09/18 13:00 | Chippa United v Orlando Pirates | W | 1-3 |
| South Africa Premier | 2021/09/11 13:00 | Orlando Pirates v Moroka Swallows | W | 1-0 |
| South Africa Premier | 2021/08/24 15:00 | Marumo Gallants v Orlando Pirates | D | 0-0 |
| South Africa Premier | 2021/08/21 13:00 | Orlando Pirates v Stellenbosch FC | D | 2-2 |
| South Africa Supa 8 Cup | 2021/08/14 16:00 | Orlando Pirates v Moroka Swallows | L | 1-2 |
| South Africa Cup | 2021/08/01 15:00 | Kaizer Chiefs v Orlando Pirates | L | 4-3 |
| South Africa Premier | 2021/06/05 13:00 | Orlando Pirates v Tshakhuma Tsha Madzivhadila | D | 0-0 |
| South Africa Premier | 2021/06/02 15:00 | Baroka FC v Orlando Pirates | W | 1-2 |
Away History
| South Africa Premier | 2021/09/19 15:00 | Mamelodi Sundowns v TS Galaxy | W | 3-0 |
| South Africa Premier | 2021/09/12 15:00 | Mamelodi Sundowns v Kaizer Chiefs | W | 2-0 |
| South Africa Supa 8 Cup | 2021/08/28 13:00 | Golden Arrows v Mamelodi Sundowns | D | 1-1 |
| South Africa Premier | 2021/08/24 15:00 | Chippa United v Mamelodi Sundowns | D | 0-0 |
| South Africa Premier | 2021/08/20 15:00 | Mamelodi Sundowns v Amazulu | W | 1-0 |
| South Africa Supa 8 Cup | 2021/08/15 13:00 | Mamelodi Sundowns v Kaizer Chiefs | W | 4-3 |
| South Africa Premier | 2021/06/05 13:00 | Mamelodi Sundowns v Cape Town City | W | 3-0 |
| South Africa Premier | 2021/06/02 15:00 | Bloem Celtic v Mamelodi Sundowns | W | 0-2 |