Head to Head
| Chile Primera Division | 2021/05/29 19:00 | La Serena v Melipilla | L | 5-1 |
| Chile Primera B | 2019/04/28 20:00 | Melipilla v La Serena | W | 4-0 |
| World Club Friendlies | 2019/02/05 20:47 | La Serena v Melipilla | D | 0-0 |
| Chile Primera B | 2018/07/29 19:30 | La Serena v Melipilla | D | 2-2 |
| Chile Primera B | 2018/03/09 21:30 | Melipilla v La Serena | W | 2-0 |
Home History
| Chile Primera Division | 2021/10/09 21:00 | CD Antofagasta v Melipilla | L | 1-0 |
| Chile Primera Division | 2021/10/04 21:30 | Melipilla v Santiago Wanderers | D | 1-1 |
| Chile Primera Division | 2021/09/30 00:00 | Universidad Catolica v Melipilla | L | 4-0 |
| Chile Primera Division | 2021/09/25 20:30 | Melipilla v Audax Italiano | D | 1-1 |
| Chile Primera Division | 2021/09/15 19:00 | Palestino v Melipilla | L | 3-1 |
| Chile Primera Division | 2021/09/07 18:00 | Melipilla v Union Espanola | L | 0-3 |
| Chile Primera Division | 2021/08/29 00:00 | Nublense v Melipilla | L | 3-0 |
| Chile Primera Division | 2021/08/25 15:30 | Melipilla v Curico Unido | D | 1-1 |
Away History
| Chile Primera Division | 2021/10/10 17:00 | La Serena v Cobresal | W | 2-1 |
| Chile Primera Division | 2021/10/05 23:30 | Nublense v La Serena | W | 0-1 |
| Chile Primera Division | 2021/09/28 19:00 | La Serena v Everton de Vina | L | 0-2 |
| Chile Primera Division | 2021/09/25 18:00 | Union Espanola v La Serena | L | 2-1 |
| Chile Primera Division | 2021/09/14 17:00 | La Serena v O'Higgins | W | 2-0 |
| Chile Primera Division | 2021/09/06 23:00 | Universidad de Chile v La Serena | D | 1-1 |
| Chile Primera Division | 2021/08/31 01:00 | Curico Unido v La Serena | L | 2-0 |
| Chile Primera Division | 2021/08/26 18:00 | La Serena v Audax Italiano | L | 0-2 |