Head to Head
| Uruguay Torneo Intermedio | 2017/07/16 19:00 | Defensor Sporting v Nacional De Football | W | 0-1 |
| Uruguay Apertura | 2017/05/06 18:30 | Defensor Sporting v Nacional De Football | L | 3-2 |
| Uruguay Apertura | 2016/11/20 22:15 | Defensor Sporting v Nacional De Football | L | 3-2 |
| Uruguay Clausura | 2016/04/10 22:00 | Defensor Sporting v Nacional De Football | W | 2-4 |
| Uruguay Apertura | 2015/10/04 21:00 | Nacional De Football v Defensor Sporting | W | 4-0 |
| Uruguay Clausura | 2015/02/15 22:00 | Defensor Sporting v Nacional De Football | D | 0-0 |
| Uruguay Apertura | 2014/08/17 19:00 | Nacional De Football v Defensor Sporting | W | 5-2 |
Home History
| World Club Friendlies | 2017/08/14 23:30 | Nacional De Football v Penarol | W | 1-0 |
| Copa Libertadores Qualification | 2017/08/10 22:15 | Botafogo v Nacional De Football | L | 2-0 |
| World Club Friendlies | 2017/07/29 23:00 | Boca Juniors v Nacional De Football | L | 4-2 |
| Uruguay Torneo Intermedio | 2017/07/16 19:00 | Defensor Sporting v Nacional De Football | W | 0-1 |
| Uruguay Torneo Intermedio | 2017/07/09 18:00 | Cerro v Nacional De Football | W | 0-2 |
| Copa Libertadores Qualification | 2017/07/07 00:45 | Nacional De Football v Botafogo | L | 0-1 |
| Uruguay Torneo Intermedio | 2017/07/01 21:00 | IA Sud America v Nacional De Football | W | 0-3 |
| Uruguay Torneo Intermedio | 2017/06/25 21:00 | Nacional De Football v Juventud De Las Piedras | W | 3-1 |
Away History
| World Club Friendlies | 2017/08/14 20:00 | Danubio v Defensor Sporting | W | 0-1 |
| Uruguay Torneo Intermedio | 2017/07/16 19:00 | Defensor Sporting v Nacional De Football | L | 0-1 |
| Uruguay Torneo Intermedio | 2017/07/08 19:00 | Penarol v Defensor Sporting | W | 2-3 |
| Uruguay Torneo Intermedio | 2017/07/02 18:00 | Plaza Colonia v Defensor Sporting | W | 0-2 |
| Uruguay Torneo Intermedio | 2017/06/25 18:00 | Defensor Sporting v Liverpool Montevideo | W | 2-0 |
| Uruguay Torneo Intermedio | 2017/06/17 18:00 | Atletico Fenix Montevideo v Defensor Sporting | D | 1-1 |
| Uruguay Torneo Intermedio | 2017/06/11 18:00 | Defensor Sporting v Boston River | W | 3-1 |
| Uruguay Torneo Intermedio | 2017/06/04 18:00 | Rampla Juniors v Defensor Sporting | W | 1-2 |