[63] Iowa State 33-20 Kansas State [66] 2021-10-16 23:30
Stadium: Bill Snyder Football Stadium Round: 1
Home Manager: Chris Klieman Away Manager: Matt Campbell
Head to Head
| NCAAF | 2020/11/21 21:00 | Kansas State v Iowa State | W | 0-45 |
| NCAAF | 2019/12/01 00:00 | Iowa State v Kansas State | L | 17-27 |
| NCAAF | 2018/11/25 00:00 | Kansas State v Iowa State | W | 38-42 |
| NCAAF | 2017/11/25 20:30 | Iowa State v Kansas State | L | 19-20 |
| NCAAF | 2016/10/29 16:00 | Kansas State v Iowa State | L | 31-26 |
| NCAAF | 2015/11/21 17:00 | Kansas State v Iowa State | L | 38-35 |
| NCAAF | 2014/09/06 16:00 | Iowa State v Kansas State | L | 28-32 |
| NCAAF | 2012/10/13 12:00 | Iowa State v Kansas State | L | 21-27 |
Home History
| NCAAF | 2021/10/02 23:00 | Kansas v Iowa State | W | 7-59 |
| NCAAF | 2021/09/25 19:30 | Iowa State v Baylor | L | 29-31 |
| NCAAF | 2021/09/19 02:30 | Iowa State v UNLV | W | 48-3 |
| NCAAF | 2021/09/11 20:30 | Iowa v Iowa State | L | 27-17 |
| NCAAF | 2021/09/04 20:30 | Northern Iowa v Iowa State | W | 10-16 |
| NCAAF | 2021/01/02 21:00 | Oregon v Iowa State | W | 17-34 |
| NCAAF | 2020/12/19 17:00 | Oklahoma v Iowa State | L | 27-21 |
| NCAAF | 2020/12/05 20:30 | West Virginia v Iowa State | W | 6-42 |
Away History
| NCAAF | 2021/10/02 19:30 | Oklahoma v Kansas State | L | 37-31 |
| NCAAF | 2021/09/25 23:00 | Kansas State v Oklahoma State | L | 20-31 |
| NCAAF | 2021/09/18 18:05 | Nevada v Kansas State | W | 17-38 |
| NCAAF | 2021/09/11 23:00 | SO Illinois v Kansas State | W | 23-31 |
| NCAAF | 2021/09/04 16:00 | Stanford v Kansas State | W | 7-24 |
| NCAAF | 2020/12/05 17:00 | Texas v Kansas State | L | 69-31 |
| NCAAF | 2020/11/29 00:00 | Kansas State v Baylor | L | 31-32 |
| NCAAF | 2020/11/21 21:00 | Kansas State v Iowa State | L | 0-45 |