Stadium: Tucker Stadium Round: 1
Home Manager: Dewayne Alexander Away Manager: Clay Hendrix
| NCAAF | 2021/09/04 18:00 | North Carolina A&T v Furman | W | 18-29 |
| NCAAF | 2021/04/10 17:00 | Furman v The Citadel | L | 7-26 |
| NCAAF | 2021/04/03 19:30 | Furman v Mercer | L | 14-26 |
| NCAAF | 2021/03/20 16:00 | Tennessee Chattanooga v Furman | L | 20-18 |
| NCAAF | 2021/03/13 18:00 | Furman v East Tennessee State | W | 17-13 |
| NCAAF | 2021/03/06 18:00 | Samford v Furman | W | 37-44 |
| NCAAF | 2021/02/27 18:30 | Furman v VMI | L | 13-14 |
| NCAAF | 2021/02/20 19:00 | Western Carolina v Furman | W | 7-35 |
| NCAAF | 2021/09/02 23:00 | Tennessee Tech v Samford | L | 14-52 |
| NCAAF | 2021/04/11 20:00 | Tennessee Tech v Tennessee Martin | L | 7-40 |
| NCAAF | 2021/04/03 18:30 | Tennessee State v Tennessee Tech | W | 10-24 |
| NCAAF | 2021/03/28 19:00 | Tennessee Tech v SE Missouri St | L | 21-24 |
| NCAAF | 2021/03/21 18:00 | Tennessee Tech v Eastern Illinois | L | 20-28 |
| NCAAF | 2021/03/14 18:30 | Murray State v Tennessee Tech | L | 36-31 |
| NCAAF | 2021/02/28 21:00 | Tennessee Tech v Jacksonville State | L | 10-27 |
| NCAAF | 2021/02/21 19:30 | Austin Peay v Tennessee Tech | W | 21-27 |