Southeastern Louisiana 38-35 McNeese State 2021-10-02 17:00
Stadium: Cowboy Stadium Round: 1
Home Manager: Frank Wilson Away Manager: Frank Scelfo
Head to Head
| NCAAF | 2021/03/07 00:00 | McNeese State v SE Louisiana | W | 20-25 |
| NCAAF | 2019/10/05 21:00 | SE Louisiana v McNeese State | L | 34-38 |
| NCAAF FCS | 2018/11/03 19:30 | McNeese State v SE Louisiana | W | 6-23 |
| NCAAF | 2017/11/04 23:00 | McNeese State v SE Louisiana | L | 13-3 |
Home History
| NCAAF | 2021/09/18 16:00 | SE Louisiana v Central Connecticut | W | 56-10 |
| NCAAF | 2021/09/11 23:00 | SE Louisiana v Louisiana Tech | L | 42-45 |
| NCAAF | 2021/09/04 23:00 | SE Louisiana v North Alabama | W | 49-28 |
| NCAAF | 2021/04/17 17:00 | SE Louisiana v SO Illinois | L | 48-55 |
| NCAAF | 2021/04/10 20:00 | SE Louisiana v Nicholls State | W | 52-45 |
| NCAAF | 2021/04/03 23:00 | Lamar v SE Louisiana | W | 12-42 |
| NCAAF | 2021/03/20 19:00 | SE Louisiana v Incarnate Word | L | 45-56 |
| NCAAF | 2021/03/14 00:00 | Northwestern State v SE Louisiana | W | 24-27 |
Away History
| NCAAF | 2021/09/25 16:00 | McNeese State v Incarnate Word | L | 0-31 |
| NCAAF | 2021/09/18 23:00 | McNeese State v Southern | W | 31-24 |
| NCAAF | 2021/09/12 00:00 | McNeese State v LSU | L | 7-34 |
| NCAAF | 2021/09/04 17:00 | McNeese State v West Florida | L | 36-42 |
| NCAAF | 2021/04/10 21:00 | McNeese State v Sam Houston State | L | 13-27 |
| NCAAF | 2021/04/03 17:00 | Nicholls State v McNeese State | W | 31-43 |
| NCAAF | 2021/03/20 21:00 | McNeese State v Northwestern State | W | 21-7 |
| NCAAF | 2021/03/13 18:00 | Lamar v McNeese State | L | 27-26 |