Stadium: Bob Waters Field at E.J. Whitmire Stadium Round: 1
| NCAAF | 2021/02/27 18:00 | Western Carolina v Samford | W | 27-55 |
| NCAAF | 2019/11/16 19:00 | Samford v Western Carolina | W | 31-13 |
| NCAAF | 2018/10/06 17:30 | Western Carolina v Samford | W | 28-66 |
| NCAAF | 2017/09/23 19:30 | Western Carolina v Samford | L | 38-34 |
| NCAAF | 2021/09/11 23:00 | Samford v Tennessee Martin | L | 27-33 |
| NCAAF | 2021/09/02 23:00 | Tennessee Tech v Samford | W | 14-52 |
| NCAAF | 2021/04/17 17:00 | Mercer v Samford | W | 20-44 |
| NCAAF | 2021/03/27 17:00 | Samford v The Citadel | W | 55-7 |
| NCAAF | 2021/03/20 17:00 | VMI v Samford | L | 38-37 |
| NCAAF | 2021/03/13 18:00 | Wofford v Samford | W | 31-37 |
| NCAAF | 2021/03/06 18:00 | Samford v Furman | L | 37-44 |
| NCAAF | 2021/02/27 18:00 | Western Carolina v Samford | W | 27-55 |
| NCAAF | 2021/09/11 23:00 | Western Carolina v Oklahoma | L | 0-76 |
| NCAAF | 2021/09/04 22:00 | Eastern Kentucky v Western Carolina | L | 31-28 |
| NCAAF | 2021/03/27 17:00 | Western Carolina v East Tennessee State | L | 17-24 |
| NCAAF | 2021/03/20 20:00 | Mercer v Western Carolina | L | 45-28 |
| NCAAF | 2021/03/13 18:00 | The Citadel v Western Carolina | W | 14-21 |
| NCAAF | 2021/03/06 18:00 | VMI v Western Carolina | L | 30-7 |
| NCAAF | 2021/02/27 18:00 | Western Carolina v Samford | L | 27-55 |
| NCAAF | 2021/02/20 19:00 | Western Carolina v Furman | L | 7-35 |