McNeese State 35-17 Northwestern State 2021-10-16 20:00
Stadium: Harry Turpin Stadium Round: 1
Home Manager: Brad Laird Away Manager: Frank Wilson
Head to Head
| NCAAF | 2021/03/20 21:00 | McNeese State v Northwestern State | W | 21-7 |
| NCAAF | 2019/11/02 21:00 | Northwestern State v McNeese State | W | 20-30 |
| NCAAF FCS | 2018/11/11 00:00 | McNeese State v Northwestern State | L | 34-37 |
| NCAAF | 2017/11/12 00:00 | McNeese State v Northwestern State | W | 44-24 |
Home History
| NCAAF | 2021/10/02 17:00 | SE Louisiana v McNeese State | L | 38-35 |
| NCAAF | 2021/09/25 16:00 | McNeese State v Incarnate Word | L | 0-31 |
| NCAAF | 2021/09/18 23:00 | McNeese State v Southern | W | 31-24 |
| NCAAF | 2021/09/12 00:00 | McNeese State v LSU | L | 7-34 |
| NCAAF | 2021/09/04 17:00 | McNeese State v West Florida | L | 36-42 |
| NCAAF | 2021/04/10 21:00 | McNeese State v Sam Houston State | L | 13-27 |
| NCAAF | 2021/04/03 17:00 | Nicholls State v McNeese State | W | 31-43 |
| NCAAF | 2021/03/20 21:00 | McNeese State v Northwestern State | W | 21-7 |
Away History
| NCAAF | 2021/10/09 23:00 | Northwestern State v Houston Christian | W | 21-17 |
| NCAAF | 2021/10/02 23:00 | Incarnate Word v Northwestern State | L | 38-27 |
| NCAAF | 2021/09/18 23:00 | Tennessee Martin v Northwestern State | L | 35-10 |
| NCAAF | 2021/09/11 23:00 | Northwestern State v Alcorn State | L | 10-13 |
| NCAAF | 2021/09/04 23:30 | Northwestern State v North Texas | L | 14-44 |
| NCAAF | 2021/04/11 00:00 | Northwestern State v Incarnate Word | W | 49-47 |
| NCAAF | 2021/04/01 23:00 | Sam Houston State v Northwestern State | L | 24-16 |
| NCAAF | 2021/03/27 20:00 | Northwestern State v Lamar | L | 23-31 |