Penn State 27-30 Michigan State 2021-11-27 20:30
Stadium: Spartan Stadium Round: 1
Home Manager: Melvin Tucker Away Manager: James Franklin
Head to Head
| NCAAF | 2020/12/12 17:00 | Michigan State v Penn State | W | 24-39 |
| NCAAF | 2019/10/26 19:30 | Penn State v Michigan State | W | 28-7 |
| NCAAF | 2018/10/13 19:30 | Michigan State v Penn State | L | 21-17 |
| NCAAF | 2017/11/04 16:00 | Penn State v Michigan State | L | 24-27 |
| NCAAF | 2016/11/26 20:30 | Michigan State v Penn State | W | 12-45 |
| NCAAF | 2015/11/28 20:30 | Michigan State v Penn State | L | 55-16 |
| NCAAF | 2014/11/29 20:30 | Penn State v Michigan State | L | 10-34 |
| NCAAF | 2010/11/27 12:00 | Penn State v Michigan State | L | 22-28 |
Home History
| NCAAF | 2021/11/20 17:00 | Rutgers v Penn State | W | 0-28 |
| NCAAF | 2021/11/13 17:00 | Michigan v Penn State | L | 21-17 |
| NCAAF | 2021/11/06 19:30 | Penn State v Maryland | W | 31-14 |
| NCAAF | 2021/10/30 23:30 | Penn State v Ohio State | L | 24-33 |
| NCAAF | 2021/10/23 16:00 | Illinois v Penn State | L | 20-18 |
| NCAAF | 2021/10/09 20:00 | Penn State v Iowa | L | 20-23 |
| NCAAF | 2021/10/02 23:30 | Indiana v Penn State | W | 0-24 |
| NCAAF | 2021/09/25 16:00 | Villanova v Penn State | W | 17-38 |
Away History
| NCAAF | 2021/11/20 17:00 | Michigan State v Ohio State | L | 7-56 |
| NCAAF | 2021/11/13 21:00 | Maryland v Michigan State | W | 21-40 |
| NCAAF | 2021/11/06 19:30 | Michigan State v Purdue | L | 29-40 |
| NCAAF | 2021/10/30 16:00 | Michigan v Michigan State | W | 33-37 |
| NCAAF | 2021/10/16 16:00 | Michigan State v Indiana | W | 20-15 |
| NCAAF | 2021/10/09 16:00 | Michigan State v Rutgers | W | 31-13 |
| NCAAF | 2021/10/02 23:30 | Western Kentucky v Michigan State | W | 31-48 |
| NCAAF | 2021/09/25 23:00 | Nebraska v Michigan State | W | 20-23 |