[11] Penn State 20-23 Iowa [7] 2021-10-09 20:00
Stadium: Kinnick Stadium Round: 1
Home Manager: Kirk Ferentz Away Manager: James Franklin
Head to Head
| NCAAF | 2020/11/21 20:30 | Iowa v Penn State | L | 41-21 |
| NCAAF | 2019/10/12 23:30 | Penn State v Iowa | W | 17-12 |
| NCAAF | 2018/10/27 19:30 | Iowa v Penn State | W | 24-30 |
| NCAAF | 2017/09/23 23:30 | Penn State v Iowa | W | 21-19 |
| NCAAF | 2016/11/05 23:30 | Iowa v Penn State | W | 14-41 |
| NCAAF | 2012/10/20 12:00 | Iowa v Penn State | W | 14-38 |
| NCAAF | 2011/10/08 12:00 | Penn State v Iowa | W | 13-3 |
| NCAAF | 2010/10/02 12:00 | Iowa v Penn State | L | 24-3 |
Home History
| NCAAF | 2021/10/02 23:30 | Indiana v Penn State | W | 0-24 |
| NCAAF | 2021/09/25 16:00 | Villanova v Penn State | W | 17-38 |
| NCAAF | 2021/09/18 23:30 | Auburn v Penn State | W | 20-28 |
| NCAAF | 2021/09/11 19:30 | Ball State v Penn State | W | 13-44 |
| NCAAF | 2021/09/04 16:00 | Penn State v Wisconsin | W | 16-10 |
| NCAAF | 2020/12/19 22:30 | Illinois v Penn State | W | 21-56 |
| NCAAF | 2020/12/12 17:00 | Michigan State v Penn State | W | 24-39 |
| NCAAF | 2020/12/05 17:00 | Penn State v Rutgers | W | 23-7 |
Away History
| NCAAF | 2021/10/02 00:00 | Iowa v Maryland | W | 51-14 |
| NCAAF | 2021/09/25 19:30 | Colorado State v Iowa | W | 14-24 |
| NCAAF | 2021/09/18 19:30 | Kent State v Iowa | W | 7-30 |
| NCAAF | 2021/09/11 20:30 | Iowa v Iowa State | W | 27-17 |
| NCAAF | 2021/09/04 19:30 | Indiana v Iowa | W | 6-34 |
| NCAAF | 2020/12/12 20:30 | Wisconsin v Iowa | W | 7-28 |
| NCAAF | 2020/12/05 20:30 | Iowa v Illinois | W | 35-21 |
| NCAAF | 2020/11/27 18:00 | Nebraska v Iowa | W | 20-26 |