[117] South Florida 14-45 Tulane [126] 2021-11-20 17:00
Stadium: Yulman Stadium Round: 1
Home Manager: Willie Fritz Away Manager: Jeff Scott
Head to Head
| NCAAF | 2018/11/03 19:30 | Tulane v South Florida | L | 41-15 |
| NCAAF | 2017/10/21 23:00 | South Florida v Tulane | W | 34-28 |
Home History
| NCAAF | 2021/11/12 23:00 | Cincinnati v South Florida | L | 45-28 |
| NCAAF | 2021/11/06 23:30 | Houston v South Florida | L | 54-42 |
| NCAAF | 2021/10/28 23:30 | South Florida v East Carolina | L | 14-29 |
| NCAAF | 2021/10/23 23:00 | Temple v South Florida | W | 14-34 |
| NCAAF | 2021/10/16 16:00 | Tulsa v South Florida | L | 32-31 |
| NCAAF | 2021/10/02 20:00 | South Florida v SMU | L | 17-41 |
| NCAAF | 2021/09/26 02:15 | South Florida v BYU | L | 27-35 |
| NCAAF | 2021/09/18 23:00 | Florida A&M v South Florida | W | 17-38 |
Away History
| NCAAF | 2021/11/13 21:00 | Tulsa v Tulane | L | 20-13 |
| NCAAF | 2021/11/06 20:00 | Tulane v Central Florida | L | 10-14 |
| NCAAF | 2021/10/30 16:00 | Cincinnati v Tulane | L | 31-12 |
| NCAAF | 2021/10/21 23:30 | Tulane v SMU | L | 26-55 |
| NCAAF | 2021/10/07 23:30 | Houston v Tulane | L | 40-22 |
| NCAAF | 2021/10/02 19:30 | Tulane v East Carolina | L | 29-52 |
| NCAAF | 2021/09/26 00:00 | UAB v Tulane | L | 28-21 |
| NCAAF | 2021/09/19 00:00 | Tulane v Mississippi | L | 21-61 |