[3] Villanova 17-38 Penn State [25] 2021-09-25 16:00
Stadium: Beaver Stadium Round: 1
Home Manager: James Franklin Away Manager: Mark Ferrante
Home History
| NCAAF | 2021/09/18 19:30 | Richmond v Villanova | W | 27-34 |
| NCAAF | 2021/09/11 22:00 | Bucknell v Villanova | W | 3-55 |
| NCAAF | 2021/09/04 16:00 | Villanova v Lehigh | W | 47-3 |
| NCAAF | 2021/04/17 17:00 | Delaware v Villanova | L | 27-20 |
| NCAAF | 2021/04/03 16:00 | Villanova v Maine | W | 44-17 |
| NCAAF | 2021/03/13 18:00 | Rhode Island v Villanova | L | 40-37 |
| NCAAF | 2021/03/06 17:00 | Villanova v Stony Brook | W | 16-13 |
| NCAAF | 2019/11/30 21:00 | Villanova v SE Louisiana | L | 44-45 |
Away History
| NCAAF | 2021/09/18 23:30 | Auburn v Penn State | W | 20-28 |
| NCAAF | 2021/09/11 19:30 | Ball State v Penn State | W | 13-44 |
| NCAAF | 2021/09/04 16:00 | Penn State v Wisconsin | W | 16-10 |
| NCAAF | 2020/12/19 22:30 | Illinois v Penn State | W | 21-56 |
| NCAAF | 2020/12/12 17:00 | Michigan State v Penn State | W | 24-39 |
| NCAAF | 2020/12/05 17:00 | Penn State v Rutgers | W | 23-7 |
| NCAAF | 2020/11/28 17:00 | Penn State v Michigan | W | 27-17 |
| NCAAF | 2020/11/21 20:30 | Iowa v Penn State | L | 41-21 |