[40] Florida 42-20 South Florida [126] 2021-09-11 17:00
Stadium: Raymond James Stadium Round: 1
Home Manager: Jeff Scott Away Manager: Dan Mullen
Home History
| NCAAF | 2021/09/04 23:30 | Florida Atlantic v Florida | W | 14-35 |
| NCAAF | 2020/12/31 01:00 | Florida v Oklahoma | L | 20-55 |
| NCAAF | 2020/12/20 01:00 | Alabama v Florida | L | 52-46 |
| NCAAF | 2020/12/13 00:00 | LSU v Florida | L | 37-34 |
| NCAAF | 2020/12/05 20:30 | Florida v Tennessee | W | 31-19 |
| NCAAF | 2020/11/28 17:00 | Kentucky v Florida | W | 10-34 |
| NCAAF | 2020/11/21 17:00 | Florida v Vanderbilt | W | 38-17 |
| NCAAF | 2020/11/15 00:00 | Arkansas v Florida | W | 35-63 |
Away History
| NCAAF | 2021/09/02 23:30 | South Florida v NC State | L | 0-45 |
| NCAAF | 2020/11/27 20:30 | Central Florida v South Florida | L | 58-46 |
| NCAAF | 2020/11/14 20:30 | South Florida v Houston | L | 21-56 |
| NCAAF | 2020/11/07 17:00 | South Florida v Memphis | L | 33-34 |
| NCAAF | 2020/10/23 23:30 | Tulsa v South Florida | L | 42-13 |
| NCAAF | 2020/10/17 16:00 | South Florida v Temple | L | 37-39 |
| NCAAF | 2020/10/10 23:00 | East Carolina v South Florida | L | 44-24 |
| NCAAF | 2020/10/03 19:30 | South Florida v Cincinnati | L | 7-28 |