[59] Central Florida 21-56 Cincinnati [12] 2021-10-16 16:00
Stadium: Nippert Stadium Round: 1
Home Manager: Luke Fickell Away Manager: Gus Malzahn
Head to Head
| NCAAF | 2020/11/21 20:30 | Cincinnati v Central Florida | L | 36-33 |
| NCAAF | 2019/10/05 00:00 | Central Florida v Cincinnati | L | 24-27 |
| NCAAF | 2018/11/18 01:00 | Cincinnati v Central Florida | W | 13-38 |
| NCAAF | 2017/10/08 00:00 | Cincinnati v Central Florida | W | 23-51 |
| NCAAF | 2016/11/12 17:00 | Cincinnati v Central Florida | W | 3-24 |
| NCAAF | 2015/10/31 16:00 | Cincinnati v Central Florida | L | 52-7 |
Home History
| NCAAF | 2021/10/09 22:00 | East Carolina v Central Florida | W | 16-20 |
| NCAAF | 2021/10/02 19:30 | Central Florida v Navy | L | 30-34 |
| NCAAF | 2021/09/17 23:30 | Central Florida v Louisville | L | 35-42 |
| NCAAF | 2021/09/11 22:30 | Bethune Cookman v Central Florida | W | 14-63 |
| NCAAF | 2021/09/02 23:00 | Boise State v Central Florida | W | 31-36 |
| NCAAF | 2020/12/23 00:00 | Central Florida v BYU | L | 23-49 |
| NCAAF | 2020/11/27 20:30 | Central Florida v South Florida | W | 58-46 |
| NCAAF | 2020/11/21 20:30 | Cincinnati v Central Florida | L | 36-33 |
Away History
| NCAAF | 2021/10/08 23:00 | Temple v Cincinnati | W | 3-52 |
| NCAAF | 2021/10/02 18:30 | Cincinnati v Notre Dame | W | 24-13 |
| NCAAF | 2021/09/18 16:00 | Cincinnati v Indiana | W | 38-24 |
| NCAAF | 2021/09/11 19:30 | Murray State v Cincinnati | W | 7-42 |
| NCAAF | 2021/09/04 19:30 | Miami Ohio v Cincinnati | W | 14-49 |
| NCAAF | 2021/01/01 17:00 | Cincinnati v Georgia | L | 21-24 |
| NCAAF | 2020/12/20 01:00 | Tulsa v Cincinnati | W | 24-27 |
| NCAAF | 2020/11/21 20:30 | Cincinnati v Central Florida | W | 36-33 |