[18] Toledo 29-32 Notre Dame [71] 2021-09-11 18:30
Stadium: Notre Dame Stadium Round: 1
Home Manager: Brian Kelly Away Manager: Jason Candle
Home History
| NCAAF | 2021/09/04 23:00 | Norfolk State v Toledo | W | 10-49 |
| NCAAF | 2020/12/12 20:00 | Central Michigan v Toledo | W | 23-24 |
| NCAAF | 2020/12/05 17:00 | Toledo v Northern Illinois | W | 41-24 |
| NCAAF | 2020/11/28 17:00 | Ball State v Toledo | L | 27-24 |
| NCAAF | 2020/11/19 00:00 | Toledo v Eastern Michigan | W | 45-28 |
| NCAAF | 2020/11/12 01:00 | Toledo v Western Michigan | L | 38-41 |
| NCAAF | 2020/11/05 01:00 | Bowling Green v Toledo | W | 3-38 |
| NCAAF | 2019/11/29 17:00 | Toledo v Central Michigan | L | 7-49 |
Away History
| NCAAF | 2021/09/05 23:30 | Notre Dame v Florida State | W | 41-38 |
| NCAAF | 2021/01/01 21:00 | Notre Dame v Alabama | L | 14-31 |
| NCAAF | 2020/12/19 21:00 | Clemson v Notre Dame | L | 34-10 |
| NCAAF | 2020/12/05 19:30 | Syracuse v Notre Dame | W | 21-45 |
| NCAAF | 2020/11/27 20:30 | Notre Dame v North Carolina | W | 31-17 |
| NCAAF | 2020/11/14 20:30 | Notre Dame v Boston College | W | 45-31 |
| NCAAF | 2020/11/08 00:30 | Clemson v Notre Dame | W | 40-47 |
| NCAAF | 2020/10/31 19:30 | Notre Dame v Georgia Tech | W | 31-13 |