[47] Eastern Michigan 10-31 Central Michigan [46] 2021-11-26 17:00
Stadium: Kelly/Shorts Stadium Round: 1
Home Manager: Jim McElwain Away Manager: Chris Creighton
Head to Head
| NCAAF | 2020/11/27 21:00 | Central Michigan v Eastern Michigan | L | 31-23 |
| NCAAF | 2019/10/05 19:00 | Eastern Michigan v Central Michigan | L | 16-42 |
| NCAAF | 2018/11/03 16:00 | Central Michigan v Eastern Michigan | W | 7-17 |
| NCAAF | 2017/11/09 01:00 | Eastern Michigan v Central Michigan | L | 30-42 |
| NCAAF | 2016/11/23 00:00 | Central Michigan v Eastern Michigan | W | 21-26 |
| NCAAF | 2015/11/27 18:00 | Central Michigan v Eastern Michigan | L | 35-28 |
| NCAAF | 2014/11/01 17:00 | Eastern Michigan v Central Michigan | L | 7-38 |
| NCAAF | 2012/11/10 12:00 | Eastern Michigan v Central Michigan | L | 31-34 |
Home History
| NCAAF | 2021/11/17 00:30 | Western Michigan v Eastern Michigan | W | 21-22 |
| NCAAF | 2021/11/10 01:00 | Ohio v Eastern Michigan | L | 34-26 |
| NCAAF | 2021/11/02 23:30 | Eastern Michigan v Toledo | W | 52-49 |
| NCAAF | 2021/10/23 16:00 | Eastern Michigan v Bowling Green | W | 55-24 |
| NCAAF | 2021/10/16 18:00 | Ball State v Eastern Michigan | L | 38-31 |
| NCAAF | 2021/10/09 19:30 | Miami Ohio v Eastern Michigan | W | 12-13 |
| NCAAF | 2021/10/02 18:30 | Eastern Michigan v Northern Illinois | L | 20-27 |
| NCAAF | 2021/09/25 18:00 | Texas State v Eastern Michigan | W | 21-59 |
Away History
| NCAAF | 2021/11/18 00:00 | Central Michigan v Ball State | W | 37-17 |
| NCAAF | 2021/11/11 01:00 | Kent State v Central Michigan | W | 30-54 |
| NCAAF | 2021/11/03 23:00 | Central Michigan v Western Michigan | W | 42-30 |
| NCAAF | 2021/10/23 16:00 | Northern Illinois v Central Michigan | L | 39-38 |
| NCAAF | 2021/10/16 19:30 | Toledo v Central Michigan | W | 23-26 |
| NCAAF | 2021/10/09 19:30 | Central Michigan v Ohio | W | 30-27 |
| NCAAF | 2021/10/02 19:30 | Central Michigan v Miami Ohio | L | 17-28 |
| NCAAF | 2021/09/25 16:00 | Florida Intl v Central Michigan | W | 27-31 |