Houston 45-17 Connecticut 2021-11-27 17:00
Stadium: Pratt and Whitney Stadium at Rentschler Field Round: 1
Home Manager: Lou Spanos Away Manager: Dana Holgorsen
Head to Head
| NCAAF | 2019/10/19 16:00 | Houston v Connecticut | W | 24-17 |
| NCAAF | 2016/09/30 00:00 | Connecticut v Houston | W | 14-42 |
| NCAAF | 2015/11/21 20:30 | Connecticut v Houston | L | 20-17 |
Home History
| NCAAF | 2021/11/20 02:00 | Memphis v Houston | W | 13-31 |
| NCAAF | 2021/11/13 17:00 | Houston v Temple | W | 37-8 |
| NCAAF | 2021/11/06 23:30 | Houston v South Florida | W | 54-42 |
| NCAAF | 2021/10/30 23:00 | SMU v Houston | W | 37-44 |
| NCAAF | 2021/10/24 01:20 | East Carolina v Houston | W | 24-31 |
| NCAAF | 2021/10/07 23:30 | Houston v Tulane | W | 40-22 |
| NCAAF | 2021/10/01 23:30 | Houston v Tulsa | W | 45-10 |
| NCAAF | 2021/09/25 23:00 | Navy v Houston | W | 20-28 |
Away History
| NCAAF | 2021/11/20 21:00 | Connecticut v Central Florida | L | 17-49 |
| NCAAF | 2021/11/13 17:00 | Connecticut v Clemson | L | 7-44 |
| NCAAF | 2021/10/22 22:00 | Middle Tennessee St. v Connecticut | L | 44-13 |
| NCAAF | 2021/10/16 16:00 | Yale v Connecticut | W | 15-21 |
| NCAAF | 2021/10/09 19:30 | Connecticut v Massachusetts | L | 13-27 |
| NCAAF | 2021/10/02 23:30 | Connecticut v Vanderbilt | L | 28-30 |
| NCAAF | 2021/09/25 19:30 | Wyoming v Connecticut | L | 24-22 |
| NCAAF | 2021/09/18 16:00 | Connecticut v Army | L | 21-52 |