Head to Head
| NCAAF | 2020/10/24 16:00 | Syracuse v Clemson | W | 21-47 |
| NCAAF | 2019/09/14 23:30 | Clemson v Syracuse | W | 41-6 |
| NCAAF | 2018/09/29 16:00 | Syracuse v Clemson | W | 23-27 |
| NCAAF | 2017/10/13 23:00 | Clemson v Syracuse | L | 24-27 |
| NCAAF | 2016/11/05 19:30 | Syracuse v Clemson | W | 0-54 |
| NCAAF | 2015/11/14 20:30 | Syracuse v Clemson | W | 27-37 |
| NCAAF | 2014/10/25 23:00 | Clemson v Syracuse | W | 16-6 |
Home History
| NCAAF | 2021/10/02 23:30 | Boston College v Clemson | W | 13-19 |
| NCAAF | 2021/09/25 19:30 | Clemson v NC State | L | 21-27 |
| NCAAF | 2021/09/18 19:30 | Georgia Tech v Clemson | W | 8-14 |
| NCAAF | 2021/09/11 21:00 | South Carolina State v Clemson | W | 3-49 |
| NCAAF | 2021/09/04 23:30 | Georgia v Clemson | L | 10-3 |
| NCAAF | 2021/01/02 01:00 | Ohio State v Clemson | L | 49-28 |
| NCAAF | 2020/12/19 21:00 | Clemson v Notre Dame | W | 34-10 |
| NCAAF | 2020/12/06 00:30 | Clemson v Virginia Tech | W | 45-10 |
Away History
| NCAAF | 2021/10/09 19:30 | Wake Forest v Syracuse | L | 40-37 |
| NCAAF | 2021/10/02 19:30 | Syracuse v Florida State | L | 30-33 |
| NCAAF | 2021/09/25 00:00 | Liberty v Syracuse | W | 21-24 |
| NCAAF | 2021/09/18 16:00 | Albany v Syracuse | W | 24-62 |
| NCAAF | 2021/09/11 18:00 | Rutgers v Syracuse | L | 17-7 |
| NCAAF | 2021/09/04 23:00 | Syracuse v Ohio | W | 29-9 |
| NCAAF | 2020/12/05 19:30 | Syracuse v Notre Dame | L | 21-45 |
| NCAAF | 2020/11/28 17:00 | NC State v Syracuse | L | 36-29 |