[89] Central Michigan 42-30 Western Michigan [49] 2021-11-03 23:00
Stadium: Waldo Stadium Round: 1
Home Manager: Tim Lester Away Manager: Jim McElwain
Head to Head
| NCAAF | 2020/11/19 00:00 | Western Michigan v Central Michigan | L | 52-44 |
| NCAAF | 2019/09/28 16:00 | Central Michigan v Western Michigan | L | 15-31 |
| NCAAF | 2018/10/20 19:00 | Western Michigan v Central Michigan | L | 35-10 |
| NCAAF | 2017/11/02 00:00 | Central Michigan v Western Michigan | W | 35-28 |
| NCAAF | 2016/10/01 23:00 | Western Michigan v Central Michigan | L | 49-10 |
| NCAAF | 2015/10/10 16:00 | Western Michigan v Central Michigan | L | 41-39 |
| NCAAF | 2014/11/22 18:00 | Central Michigan v Western Michigan | L | 20-32 |
| NCAAF | 2012/11/03 12:00 | Central Michigan v Western Michigan | L | 31-42 |
Home History
| NCAAF | 2021/10/23 16:00 | Northern Illinois v Central Michigan | L | 39-38 |
| NCAAF | 2021/10/16 19:30 | Toledo v Central Michigan | W | 23-26 |
| NCAAF | 2021/10/09 19:30 | Central Michigan v Ohio | W | 30-27 |
| NCAAF | 2021/10/02 19:30 | Central Michigan v Miami Ohio | L | 17-28 |
| NCAAF | 2021/09/25 16:00 | Florida Intl v Central Michigan | W | 27-31 |
| NCAAF | 2021/09/18 23:30 | Central Michigan v LSU | L | 21-49 |
| NCAAF | 2021/09/11 19:00 | Robert Morris v Central Michigan | W | 0-45 |
| NCAAF | 2021/09/04 20:00 | Central Michigan v Missouri | L | 24-34 |
Away History
| NCAAF | 2021/10/23 19:30 | Western Michigan v Toledo | L | 15-34 |
| NCAAF | 2021/10/16 19:30 | Kent State v Western Michigan | W | 31-64 |
| NCAAF | 2021/10/09 19:30 | Ball State v Western Michigan | L | 45-20 |
| NCAAF | 2021/10/02 16:00 | Western Michigan v Buffalo | W | 24-17 |
| NCAAF | 2021/09/25 18:00 | San Jose State v Western Michigan | W | 3-23 |
| NCAAF | 2021/09/18 16:00 | Western Michigan v Pittsburgh | W | 44-41 |
| NCAAF | 2021/09/11 21:00 | Illinois State v Western Michigan | W | 0-28 |
| NCAAF | 2021/09/04 16:00 | Western Michigan v Michigan | L | 14-47 |