[62] Wyoming 21-27 San Jose State [70] 2021-10-30 20:00
Stadium: CEFCU Stadium Round: 1
Home Manager: Brent Brennan Away Manager: Craig Bohl
Head to Head
| NCAAF | 2018/11/03 18:00 | San Jose State v Wyoming | W | 9-24 |
| NCAAF | 2017/11/25 22:00 | Wyoming v San Jose State | L | 17-20 |
| NCAAF | 2014/10/18 20:00 | Wyoming v San Jose State | L | 20-27 |
Home History
| NCAAF | 2021/10/23 19:30 | New Mexico v Wyoming | L | 14-3 |
| NCAAF | 2021/10/16 19:30 | Fresno State v Wyoming | L | 17-0 |
| NCAAF | 2021/10/09 23:00 | Wyoming v Air Force | L | 14-24 |
| NCAAF | 2021/09/25 19:30 | Wyoming v Connecticut | W | 24-22 |
| NCAAF | 2021/09/18 20:00 | Ball State v Wyoming | W | 12-45 |
| NCAAF | 2021/09/11 17:30 | Wyoming v Northern Illinois | W | 50-43 |
| NCAAF | 2021/09/04 20:00 | Montana State v Wyoming | W | 16-19 |
| NCAAF | 2020/12/12 23:00 | Boise State v Wyoming | L | 17-9 |
Away History
| NCAAF | 2021/10/22 03:00 | San Jose State v UNLV | W | 27-20 |
| NCAAF | 2021/10/16 02:30 | San Diego State v San Jose State | L | 19-13 |
| NCAAF | 2021/10/09 19:30 | San Jose State v Colorado State | L | 14-32 |
| NCAAF | 2021/10/03 02:30 | New Mexico State v San Jose State | W | 31-37 |
| NCAAF | 2021/09/25 18:00 | San Jose State v Western Michigan | L | 3-23 |
| NCAAF | 2021/09/19 04:30 | San Jose State v Hawaii | W | 17-13 |
| NCAAF | 2021/09/04 21:00 | San Jose State v USC | L | 7-30 |
| NCAAF | 2021/08/29 02:00 | Southern Utah v San Jose State | W | 14-45 |