Eastern Illinois 26-42 Austin Peay 2021-11-06 19:00
Stadium: Fortera Stadium Round: 1
Home Manager: Marquase Lovings Away Manager: Adam Cushing
Head to Head
| NCAAF | 2019/11/23 20:00 | Eastern Illinois v Austin Peay | L | 7-35 |
| NCAAF FCS | 2018/11/10 19:00 | Austin Peay v Eastern Illinois | W | 21-52 |
| NCAAF | 2017/11/18 23:00 | Austin Peay v Eastern Illinois | L | 28-13 |
Home History
| NCAAF | 2021/10/30 18:00 | Eastern Illinois v SE Missouri St | L | 15-38 |
| NCAAF | 2021/10/23 19:00 | Tennessee State v Eastern Illinois | L | 28-0 |
| NCAAF | 2021/10/16 19:00 | Tennessee Martin v Eastern Illinois | L | 28-17 |
| NCAAF | 2021/10/02 21:00 | Eastern Illinois v Murray State | L | 6-22 |
| NCAAF | 2021/09/25 18:30 | Eastern Illinois v Tennessee Tech | W | 28-14 |
| NCAAF | 2021/09/18 23:00 | Illinois State v Eastern Illinois | L | 31-24 |
| NCAAF | 2021/09/11 17:00 | Eastern Illinois v Dayton | L | 10-17 |
| NCAAF | 2021/09/04 23:00 | Eastern Illinois v South Carolina | L | 0-46 |
Away History
| NCAAF | 2021/10/30 19:00 | Austin Peay v Tennessee Martin | L | 16-17 |
| NCAAF | 2021/10/23 19:00 | Austin Peay v Murray State | W | 47-6 |
| NCAAF | 2021/10/09 20:00 | SE Missouri St v Austin Peay | L | 30-14 |
| NCAAF | 2021/10/03 00:00 | Tennessee State v Austin Peay | L | 24-22 |
| NCAAF | 2021/09/25 19:00 | Austin Peay v Eastern Kentucky | L | 27-35 |
| NCAAF | 2021/09/18 19:00 | Morehead State v Austin Peay | W | 35-59 |
| NCAAF | 2021/09/11 23:30 | Austin Peay v Mississippi | L | 17-54 |
| NCAAF | 2021/09/02 23:30 | Austin Peay v Tennessee Chattanooga | W | 30-20 |