Southeastern Louisiana 58-48 Nicholls State 2021-10-09 17:00
Stadium: Manning Field at John L. Guidry Stadium Round: 1
Home Manager: Tim Rebowe Away Manager: Frank Scelfo
Head to Head
| NCAAF | 2021/04/10 20:00 | SE Louisiana v Nicholls State | W | 52-45 |
| NCAAF | 2019/11/22 00:00 | Nicholls State v SE Louisiana | L | 28-27 |
| NCAAF FCS | 2018/11/16 00:00 | SE Louisiana v Nicholls State | L | 0-44 |
| NCAAF | 2017/11/17 00:00 | SE Louisiana v Nicholls State | W | 21-17 |
Home History
| NCAAF | 2021/10/02 17:00 | SE Louisiana v McNeese State | W | 38-35 |
| NCAAF | 2021/09/18 16:00 | SE Louisiana v Central Connecticut | W | 56-10 |
| NCAAF | 2021/09/11 23:00 | SE Louisiana v Louisiana Tech | L | 42-45 |
| NCAAF | 2021/09/04 23:00 | SE Louisiana v North Alabama | W | 49-28 |
| NCAAF | 2021/04/17 17:00 | SE Louisiana v SO Illinois | L | 48-55 |
| NCAAF | 2021/04/10 20:00 | SE Louisiana v Nicholls State | W | 52-45 |
| NCAAF | 2021/04/03 23:00 | Lamar v SE Louisiana | W | 12-42 |
| NCAAF | 2021/03/20 19:00 | SE Louisiana v Incarnate Word | L | 45-56 |
Away History
| NCAAF | 2021/10/02 20:00 | Houston Christian v Nicholls State | W | 17-48 |
| NCAAF | 2021/09/25 20:00 | North Alabama v Nicholls State | W | 14-31 |
| NCAAF | 2021/09/11 23:00 | Nicholls State v Lafayette | L | 24-27 |
| NCAAF | 2021/09/04 23:00 | Nicholls State v Memphis | L | 17-42 |
| NCAAF | 2021/04/10 20:00 | SE Louisiana v Nicholls State | L | 52-45 |
| NCAAF | 2021/04/03 17:00 | Nicholls State v McNeese State | L | 31-43 |
| NCAAF | 2021/03/27 16:00 | Incarnate Word v Nicholls State | W | 45-75 |
| NCAAF | 2021/03/13 18:00 | Nicholls State v Sam Houston State | L | 17-71 |