Stadium: Homer Bryce Stadium Round: 1
Home Manager: Colby Carthel Away Manager: Vincent Dancy
| NCAAF | 2021/09/03 00:00 | Mississippi Valley State v Murray State | L | 0-35 |
| NCAAF | 2021/04/10 19:00 | Mississippi Valley State v Alabama State | L | 17-42 |
| NCAAF | 2021/04/03 20:00 | Arkansas Pine Bluff v Mississippi Valley State | L | 24-17 |
| NCAAF | 2021/03/14 19:00 | Mississippi Valley State v Jackson State | L | 7-43 |
| NCAAF | 2019/11/23 19:00 | Mississippi Valley State v Alabama | L | 13-30 |
| NCAAF | 2019/11/16 19:00 | Grambling State v Mississippi Valley State | L | 40-0 |
| NCAAF | 2019/11/02 18:00 | Alabama State v Mississippi Valley State | L | 27-0 |
| NCAAF | 2019/10/26 19:00 | Texas Southern Tigers v Mississippi Valley State | W | 14-35 |
| NCAAF | 2021/09/11 23:00 | Stephen F. Austin v Texas Tech | L | 22-28 |
| NCAAF | 2021/09/04 23:00 | Tarleton State v Stephen F. Austin | W | 10-20 |
| NCAAF | 2020/11/21 17:00 | Stephen F. Austin v Memphis | L | 14-56 |
| NCAAF | 2020/11/14 22:00 | Stephen F. Austin v Pittsburgh State Gorillas | W | 26-7 |
| NCAAF | 2020/11/07 20:00 | Stephen F. Austin v Eastern Kentucky | W | 24-6 |
| NCAAF | 2020/10/31 19:00 | Stephen F. Austin v Western State Colorado Mountaineers | W | 64-7 |
| NCAAF | 2020/10/24 17:30 | Stephen F. Austin v Abilene Christian | W | 35-32 |
| NCAAF | 2020/10/17 21:00 | Stephen F. Austin v Angelo State Univeristy Rams | W | 31-12 |