[12] Palermo 2-0 US Latina Calcio [11] 2021-08-29 18:30
Stadium: Renzo Barbera Round: 1
Referee: Luca Angelucci Home Manager: Giacomo Filippi Away Manager: Piero Baseli
Home History
| Italy Serie C Cup | 2021/08/21 15:30 | Palermo v AZ Picerno ASD | W | 4-1 |
| Europe Friendlies | 2021/07/29 16:00 | Palermo v Monopoli | W | 1-0 |
| Europe Friendlies | 2021/07/25 17:00 | Potenza v Palermo | W | 0-3 |
| Italy Serie C Play-Offs | 2021/05/26 18:45 | Avellino v Palermo | L | 1-0 |
| Italy Serie C Play-Offs | 2021/05/23 15:30 | Palermo v Avellino | W | 1-0 |
| Italy Serie C Play-Offs | 2021/05/19 15:30 | Juve Stabia v Palermo | W | 0-2 |
| Italy Serie C Play-Offs | 2021/05/09 13:30 | Palermo v Teramo | W | 2-0 |
| Italy Serie C Group C | 2021/05/02 18:30 | Virtus Francavilla v Palermo | W | 1-3 |
Away History
| Italy Serie C Cup | 2021/08/22 18:00 | SS Turris Calcio v US Latina Calcio | L | 1-0 |
| Italy Serie D | 2021/06/19 15:00 | US Latina Calcio v AC Savoia 1908 | D | 1-1 |
| Italy Serie D Play-Offs | 2021/06/16 16:00 | US Latina Calcio v Nocerina | D | 1-1 |
| Italy Serie D | 2021/06/13 14:00 | US Latina Calcio v Insieme Formia | W | 3-2 |
| Italy Serie D | 2021/06/09 14:00 | Nocerina v US Latina Calcio | L | 4-0 |
| Italy Serie D | 2021/06/06 14:00 | US Latina Calcio v Carbonia | W | 3-1 |
| Italy Serie D | 2021/06/02 14:00 | US Latina Calcio v ASD Muravera | W | 3-0 |
| Italy Serie D | 2021/05/30 14:00 | FC Guidonia Montecelio 1937 v US Latina Calcio | L | 2-0 |