Stadium: McPherson Memorial Stadium Round: 1
| NCAAF | 2019/11/02 19:00 | Lane College Dragons v Central State | L | 36-10 |
| NCAAF | 2018/11/03 17:00 | Central State v Lane College Dragons | W | 45-22 |
| NCAAF | 2021/10/23 18:00 | Edward Waters Tigers v Central State | L | 56-19 |
| NCAAF | 2021/10/16 17:00 | Central State v Tuskegee | L | 0-29 |
| NCAAF | 2021/10/09 18:00 | Fort Valley State v Central State | L | 35-14 |
| NCAAF | 2021/10/02 17:00 | Central State v Allen Yellow Jackets | L | 34-46 |
| NCAAF | 2021/09/25 23:00 | Miles Golden Bears v Central State | L | 55-4 |
| NCAAF | 2021/09/18 17:00 | Shaw Bears v Central State | L | 52-0 |
| NCAAF | 2021/09/11 17:00 | Lincoln University v Central State | W | 7-19 |
| NCAAF | 2021/08/28 19:00 | Central State v Kentucky Thorobreds | L | 6-20 |
| NCAAF | 2021/10/23 18:00 | Tuskegee v Lane College Dragons | W | 17-21 |
| NCAAF | 2021/10/16 19:00 | Lane College Dragons v Miles Golden Bears | L | 31-34 |
| NCAAF | 2021/10/09 18:00 | Kentucky Thorobreds v Lane College Dragons | L | 49-14 |
| NCAAF | 2021/10/02 19:00 | Lane College Dragons v Texas College Steers | W | 71-0 |
| NCAAF | 2021/09/25 22:00 | Edward Waters Tigers v Lane College Dragons | W | 35-45 |
| NCAAF | 2021/09/18 18:00 | Fort Valley State v Lane College Dragons | W | 24-27 |
| NCAAF | 2021/09/11 20:00 | Clark Atlanta University v Lane College Dragons | W | 26-35 |
| NCAAF | 2021/09/04 23:00 | Arkansas Pine Bluff v Lane College Dragons | L | 34-16 |