Stadium: Western New Mexico Ben Altamirano Field Round: 1
| NCAAF | 2021/10/31 00:00 | Midwestern State University Mustangs v Western New Mexico Mustangs | L | 52-10 |
| NCAAF | 2021/10/23 18:00 | Western New Mexico Mustangs v Texas AM Kingsville Javelinas | L | 19-28 |
| NCAAF | 2021/10/16 21:00 | Texas A&M-Commerce v Western New Mexico Mustangs | L | 58-0 |
| NCAAF | 2021/10/10 00:00 | Western New Mexico Mustangs v Eastern New Mexico University Greyhounds | L | 47-50 |
| NCAAF | 2021/10/02 23:00 | Angelo State Univeristy Rams v Western New Mexico Mustangs | L | 62-3 |
| NCAAF | 2021/09/26 00:00 | Western New Mexico Mustangs v Texas-Permian Basin Falcons | L | 19-27 |
| NCAAF | 2021/09/19 00:00 | West Texas AM Buffaloes v Western New Mexico Mustangs | L | 42-14 |
| NCAAF | 2021/09/11 18:00 | Western New Mexico Mustangs v Western State Colorado Mountaineers | L | 14-49 |
| NCAAF | 2021/10/31 01:00 | Central Washington v Lincoln Oaklanders | W | 92-0 |
| NCAAF | 2021/10/24 01:00 | Central Washington v Western Oregon | W | 53-21 |
| NCAAF | 2021/10/09 20:05 | Western Oregon v Central Washington | W | 14-45 |
| NCAAF | 2021/10/03 01:00 | Central Washington v Midwestern State University Mustangs | W | 30-20 |
| NCAAF | 2021/09/26 01:00 | Central Washington v Angelo State Univeristy Rams | L | 9-14 |
| NCAAF | 2021/09/19 01:00 | Simon Fraser Clan v Central Washington | W | 14-36 |
| NCAAF | 2021/09/11 20:00 | East Washington v Central Washington | L | 63-14 |
| NCAAF | 2021/09/03 00:00 | Eastern New Mexico University Greyhounds v Central Washington | W | 24-66 |