Stadium: First Security Stadium Round: 1
| NCAAF | 2019/10/05 23:00 | Harding Bisons v Southern Nazarene | W | 31-3 |
| NCAAF | 2018/09/15 18:00 | Southern Nazarene v Harding Bisons | W | 0-42 |
| NCAAF | 2021/10/02 19:00 | Oklahoma Baptist Bison v Harding Bisons | W | 7-31 |
| NCAAF | 2021/09/25 23:00 | Harding Bisons v Ouachita Baptist Tigers | W | 38-21 |
| NCAAF | 2021/09/18 23:00 | Southern Arkansas Muleriders v Harding Bisons | W | 6-37 |
| NCAAF | 2021/09/11 23:00 | Southeastern Oklahoma State Savage Storm v Harding Bisons | L | 32-31 |
| NCAAF | 2021/09/04 23:00 | Harding Bisons v East Central Tigers | W | 28-0 |
| NCAAF | 2019/11/23 19:00 | NW Missouri State v Harding Bisons | L | 7-6 |
| NCAAF | 2019/11/16 20:00 | Arkansas Tech Wonder Boys v Harding Bisons | W | 14-49 |
| NCAAF | 2019/11/09 20:00 | Southeastern Oklahoma State Savage Storm v Harding Bisons | W | 14-35 |
| NCAAF | 2021/10/02 18:00 | Southern Nazarene v Arkansas Tech Wonder Boys | L | 41-51 |
| NCAAF | 2021/09/25 19:00 | Southern Nazarene v Southeastern Oklahoma State Savage Storm | L | 10-31 |
| NCAAF | 2021/09/18 23:00 | East Central Tigers v Southern Nazarene | L | 40-13 |
| NCAAF | 2021/09/11 18:00 | Southern Nazarene v Ouachita Baptist Tigers | L | 3-41 |
| NCAAF | 2021/09/02 23:00 | Arkansas Monticello Boll Weevils v Southern Nazarene | L | 30-23 |
| NCAAF | 2019/11/16 19:00 | Southern Nazarene v Oklahoma Baptist Bison | L | 27-52 |
| NCAAF | 2019/11/09 21:00 | Southern Nazarene v Northwestern Oklahoma State Rangers | L | 21-35 |
| NCAAF | 2019/11/02 19:00 | Southwestern Oklahoma State Bulldogs v Southern Nazarene | L | 28-7 |