Stadium: SNU Stadium Round: 1
| NCAAF | 2019/11/16 19:00 | Southern Nazarene v Oklahoma Baptist Bison | L | 27-52 |
| NCAAF | 2018/11/10 19:00 | Oklahoma Baptist Bison v Southern Nazarene | L | 30-24 |
| NCAAF | 2021/11/06 18:00 | Southern Nazarene v Southern Arkansas Muleriders | L | 10-31 |
| NCAAF | 2021/10/30 19:00 | Henderson State Reddies v Southern Nazarene | L | 34-3 |
| NCAAF | 2021/10/23 20:00 | Northwestern Oklahoma State Rangers v Southern Nazarene | L | 47-27 |
| NCAAF | 2021/10/14 23:00 | Southern Nazarene v Southwestern Oklahoma State Bulldogs | W | 30-22 |
| NCAAF | 2021/10/09 19:00 | Harding Bisons v Southern Nazarene | L | 49-10 |
| NCAAF | 2021/10/02 18:00 | Southern Nazarene v Arkansas Tech Wonder Boys | L | 41-51 |
| NCAAF | 2021/09/25 19:00 | Southern Nazarene v Southeastern Oklahoma State Savage Storm | L | 10-31 |
| NCAAF | 2021/09/18 23:00 | East Central Tigers v Southern Nazarene | L | 40-13 |
| NCAAF | 2021/11/06 19:00 | Oklahoma Baptist Bison v Henderson State Reddies | L | 34-36 |
| NCAAF | 2021/10/30 19:00 | Southern Arkansas Muleriders v Oklahoma Baptist Bison | W | 40-44 |
| NCAAF | 2021/10/23 23:00 | Oklahoma Baptist Bison v Southeastern Oklahoma State Savage Storm | W | 43-37 |
| NCAAF | 2021/10/16 23:00 | East Central Tigers v Oklahoma Baptist Bison | W | 20-47 |
| NCAAF | 2021/10/09 19:00 | Arkansas Tech Wonder Boys v Oklahoma Baptist Bison | L | 38-35 |
| NCAAF | 2021/10/02 19:00 | Oklahoma Baptist Bison v Harding Bisons | L | 7-31 |
| NCAAF | 2021/09/25 23:00 | Southwestern Oklahoma State Bulldogs v Oklahoma Baptist Bison | W | 27-31 |
| NCAAF | 2021/09/18 23:00 | Oklahoma Baptist Bison v Northwestern Oklahoma State Rangers | W | 56-42 |