Stadium: Fred G. Hughes Stadium Round: 1
| NCAAF | 2019/09/29 00:00 | Fort Hays State University Tigers v Missouri Southern Lions | L | 44-3 |
| NCAAF | 2018/09/22 23:00 | Missouri Southern Lions v Fort Hays State University Tigers | L | 20-55 |
| NCAAF | 2021/09/19 00:00 | Central Oklahoma v Missouri Southern Lions | W | 10-14 |
| NCAAF | 2021/09/11 19:00 | Missouri Southern Lions v Northeastern State Riverhawks | L | 17-21 |
| NCAAF | 2021/09/03 00:00 | Nebraska Kearney v Missouri Southern Lions | L | 38-0 |
| NCAAF | 2019/11/16 19:00 | Pittsburgh State Gorillas v Missouri Southern Lions | L | 65-6 |
| NCAAF | 2019/11/09 21:00 | Missouri Southern Lions v Emporia State | L | 6-29 |
| NCAAF | 2019/11/02 18:00 | Central Oklahoma v Missouri Southern Lions | L | 52-27 |
| NCAAF | 2019/10/26 19:00 | Northeastern State Riverhawks v Missouri Southern Lions | W | 7-86 |
| NCAAF | 2019/10/19 21:00 | Missouri Southern Lions v Washburn Ichabods Football | L | 19-49 |
| NCAAF | 2021/09/19 00:00 | Fort Hays State University Tigers v Blue Tigers | W | 72-0 |
| NCAAF | 2021/09/10 00:00 | Missouri Western Griffons v Fort Hays State University Tigers | L | 38-31 |
| NCAAF | 2021/09/03 00:00 | Fort Hays State University Tigers v NW Missouri State | L | 7-15 |
| NCAAF | 2019/11/16 20:00 | Northeastern State Riverhawks v Fort Hays State University Tigers | W | 7-91 |
| NCAAF | 2019/11/09 20:00 | Fort Hays State University Tigers v NW Missouri State | L | 33-36 |
| NCAAF | 2019/11/02 18:00 | Blue Tigers v Fort Hays State University Tigers | W | 6-66 |
| NCAAF | 2019/10/26 19:00 | Fort Hays State University Tigers v Nebraska Kearney | W | 37-31 |
| NCAAF | 2019/10/19 18:00 | Pittsburgh State Gorillas v Fort Hays State University Tigers | W | 41-42 |