Stadium: Milam Stadium Round: 1
| NCAAF | 2019/09/14 23:00 | Southwestern Oklahoma State Bulldogs v East Central Tigers | W | 24-21 |
| NCAAF | 2018/09/29 23:00 | East Central Tigers v Southwestern Oklahoma State Bulldogs | L | 18-11 |
| NCAAF | 2021/10/14 23:00 | Southern Nazarene v Southwestern Oklahoma State Bulldogs | L | 30-22 |
| NCAAF | 2021/10/09 19:00 | Southwestern Oklahoma State Bulldogs v Ouachita Baptist Tigers | L | 10-30 |
| NCAAF | 2021/10/02 19:00 | Arkansas Monticello Boll Weevils v Southwestern Oklahoma State Bulldogs | L | 18-16 |
| NCAAF | 2021/09/25 23:00 | Southwestern Oklahoma State Bulldogs v Oklahoma Baptist Bison | L | 27-31 |
| NCAAF | 2021/09/18 23:00 | Southeastern Oklahoma State Savage Storm v Southwestern Oklahoma State Bulldogs | L | 37-28 |
| NCAAF | 2021/09/11 23:00 | Southern Arkansas Muleriders v Southwestern Oklahoma State Bulldogs | L | 42-27 |
| NCAAF | 2021/09/02 23:00 | Southwestern Oklahoma State Bulldogs v Henderson State Reddies | L | 13-31 |
| NCAAF | 2019/11/16 21:00 | Northwestern Oklahoma State Rangers v Southwestern Oklahoma State Bulldogs | L | 28-16 |
| NCAAF | 2021/10/16 23:00 | East Central Tigers v Oklahoma Baptist Bison | L | 20-47 |
| NCAAF | 2021/10/09 19:00 | Henderson State Reddies v East Central Tigers | L | 59-24 |
| NCAAF | 2021/10/02 19:00 | East Central Tigers v Southern Arkansas Muleriders | W | 38-17 |
| NCAAF | 2021/09/25 23:00 | Northwestern Oklahoma State Rangers v East Central Tigers | W | 17-20 |
| NCAAF | 2021/09/18 23:00 | East Central Tigers v Southern Nazarene | W | 40-13 |
| NCAAF | 2021/09/11 23:00 | East Central Tigers v Arkansas Tech Wonder Boys | W | 13-10 |
| NCAAF | 2021/09/04 23:00 | Harding Bisons v East Central Tigers | L | 28-0 |
| NCAAF | 2021/04/01 23:00 | Tarleton State v East Central Tigers | W | 14-21 |