Stadium: Memorial Stadium Round: 1
| NCAAF | 2019/10/05 18:00 | Clarion Golden Eagles v Seton Hill Griffins | W | 42-16 |
| NCAAF | 2018/09/29 20:00 | Seton Hill Griffins v Clarion Golden Eagles | W | 16-19 |
| NCAAF | 2021/10/09 18:00 | Clarion Golden Eagles v Iup Crimson Hawks | L | 21-58 |
| NCAAF | 2021/10/02 22:00 | Slippery Rock v Clarion Golden Eagles | L | 75-0 |
| NCAAF | 2021/09/25 17:00 | Gannon University Golden Knights v Clarion Golden Eagles | L | 56-21 |
| NCAAF | 2021/09/18 17:00 | Clarion Golden Eagles v Shippensburg Raiders | L | 33-62 |
| NCAAF | 2021/09/11 17:00 | Clarion Golden Eagles v Millersville University of Pennsylvania Marauders | L | 10-21 |
| NCAAF | 2021/09/04 22:00 | Clarion Golden Eagles v Lake Erie | L | 26-31 |
| NCAAF | 2019/11/16 18:05 | East Stroudsburg Warriors v Clarion Golden Eagles | L | 41-17 |
| NCAAF | 2019/11/09 17:00 | Clarion Golden Eagles v Mercyhurst | L | 10-57 |
| NCAAF | 2021/10/16 20:00 | Seton Hill Griffins v Gannon University Golden Knights | L | 10-14 |
| NCAAF | 2021/10/09 16:00 | Mercyhurst v Seton Hill Griffins | W | 17-19 |
| NCAAF | 2021/10/02 20:00 | Seton Hill Griffins v Edinboro | L | 7-17 |
| NCAAF | 2021/09/25 22:00 | Seton Hill Griffins v Slippery Rock | L | 17-41 |
| NCAAF | 2021/09/18 16:05 | Kutztown Golden Bears v Seton Hill Griffins | L | 14-3 |
| NCAAF | 2021/09/11 22:00 | Seton Hill Griffins v Bloomsburg Huskies | W | 13-7 |
| NCAAF | 2021/09/02 23:00 | Seton Hill Griffins v Wheeling | W | 16-14 |
| NCAAF | 2019/11/16 17:00 | Shepherd Rams v Seton Hill Griffins | L | 56-24 |