Stadium: Tullio Field Round: 1
| NCAAF | 2019/10/19 16:00 | Mercyhurst v Seton Hill Griffins | L | 20-30 |
| NCAAF | 2018/10/13 16:00 | Seton Hill Griffins v Mercyhurst | L | 34-33 |
| NCAAF | 2021/10/02 19:00 | California Vulcans v Mercyhurst | L | 37-0 |
| NCAAF | 2021/09/25 17:00 | Mercyhurst v Iup Crimson Hawks | L | 13-48 |
| NCAAF | 2021/09/18 17:05 | East Stroudsburg Warriors v Mercyhurst | L | 17-7 |
| NCAAF | 2021/09/11 16:00 | Mercyhurst v West Chester Golden Rams | L | 10-56 |
| NCAAF | 2021/09/04 22:00 | Mercyhurst v Alderson Broaddus Battlers | W | 18-3 |
| NCAAF | 2019/11/16 17:00 | Millersville University of Pennsylvania Marauders v Mercyhurst | W | 7-17 |
| NCAAF | 2019/11/09 17:00 | Clarion Golden Eagles v Mercyhurst | W | 10-57 |
| NCAAF | 2019/11/02 16:00 | Mercyhurst v Gannon University Golden Knights | W | 28-7 |
| NCAAF | 2021/10/02 20:00 | Seton Hill Griffins v Edinboro | L | 7-17 |
| NCAAF | 2021/09/25 22:00 | Seton Hill Griffins v Slippery Rock | L | 17-41 |
| NCAAF | 2021/09/18 16:05 | Kutztown Golden Bears v Seton Hill Griffins | L | 14-3 |
| NCAAF | 2021/09/11 22:00 | Seton Hill Griffins v Bloomsburg Huskies | W | 13-7 |
| NCAAF | 2021/09/02 23:00 | Seton Hill Griffins v Wheeling | W | 16-14 |
| NCAAF | 2019/11/16 17:00 | Shepherd Rams v Seton Hill Griffins | L | 56-24 |
| NCAAF | 2019/11/09 21:00 | California Vulcans v Seton Hill Griffins | L | 28-14 |
| NCAAF | 2019/11/02 16:00 | Seton Hill Griffins v Iup Crimson Hawks | L | 23-50 |