Stadium: DICK'S SPORTING GOODS FIELD Round: 1
| NCAAF | 2019/10/12 20:00 | Seton Hill Griffins v Gannon University Golden Knights | W | 25-21 |
| NCAAF | 2018/10/06 16:00 | Gannon University Golden Knights v Seton Hill Griffins | L | 48-28 |
| NCAAF | 2021/10/09 16:00 | Mercyhurst v Seton Hill Griffins | W | 17-19 |
| NCAAF | 2021/10/02 20:00 | Seton Hill Griffins v Edinboro | L | 7-17 |
| NCAAF | 2021/09/25 22:00 | Seton Hill Griffins v Slippery Rock | L | 17-41 |
| NCAAF | 2021/09/18 16:05 | Kutztown Golden Bears v Seton Hill Griffins | L | 14-3 |
| NCAAF | 2021/09/11 22:00 | Seton Hill Griffins v Bloomsburg Huskies | W | 13-7 |
| NCAAF | 2021/09/02 23:00 | Seton Hill Griffins v Wheeling | W | 16-14 |
| NCAAF | 2019/11/16 17:00 | Shepherd Rams v Seton Hill Griffins | L | 56-24 |
| NCAAF | 2019/11/09 21:00 | California Vulcans v Seton Hill Griffins | L | 28-14 |
| NCAAF | 2021/10/09 16:00 | Gannon University Golden Knights v California Vulcans | L | 17-38 |
| NCAAF | 2021/10/02 18:00 | Iup Crimson Hawks v Gannon University Golden Knights | L | 28-23 |
| NCAAF | 2021/09/25 17:00 | Gannon University Golden Knights v Clarion Golden Eagles | W | 56-21 |
| NCAAF | 2021/09/18 18:00 | Bloomsburg Huskies v Gannon University Golden Knights | L | 31-27 |
| NCAAF | 2021/09/11 16:00 | Gannon University Golden Knights v Shepherd Rams | L | 26-56 |
| NCAAF | 2021/09/02 23:00 | Northwood Timberwolves v Gannon University Golden Knights | W | 21-28 |
| NCAAF | 2019/11/16 18:00 | Lock Haven v Gannon University Golden Knights | L | 28-27 |
| NCAAF | 2019/11/09 17:00 | Gannon University Golden Knights v Slippery Rock | L | 7-56 |